Stem Cell IVF Treatment & Ovarian Rejuvenation PRP  Treatment

As a fertility specialist, one of the most difficult conversations I have with patients is when traditional treatments like IVF haven’t worked. Many women and couples tell me they feel overwhelmed and hopeless and ask:

👉 “Is there anything beyond IVF that could help me conceive with my own eggs or sperm?”

The truth is, infertility is not rare. Globally, 8–12% of couples struggle with it (WHO). For many, the cause is poor egg quality, low ovarian reserve, or reduced sperm count.

Thanks to advances in reproductive regenerative medicine, there are now innovative therapies like Stem Cell IVF Treatment and Ovarian Rejuvenation Therapy.

While still considered experimental, early research is showing promising results—offering new hope to men and women who thought they had no options left.

In India, Dr. Jay Mehta, a pioneer in reproductive regenerative medicine and founder of Shree IVF Clinic, Mumbai, is among the few specialists offering these advanced treatments. With his expertise in IVF, ovarian rejuvenation, and stem cell applications, patients from across India and overseas trust him for cutting-edge, ethical, and personalized fertility care.

In this guide, we’ll explain what these treatments are, how they work, who they’re best suited for, and what you should know before considering them.

Stem Cell IVF Therapy is an advanced fertility treatment that uses the body’s own stem cells to help regenerate sperm or egg cells. Stem cells are like the “raw materials” of our body—they can transform into different types of specialized cells, including reproductive cells.

Who it can help:

• Men with low sperm count or poor sperm quality
• Women with poor egg quality, ovarian damage, or unexplained infertility

How Does It Work?

1.   Stem Cell Collection—Stem cells are extracted from the patient’s bone marrow, adipose tissue (fat), or blood.
2.  Processing—In the lab, stem cells are isolated and prepared for use.
3.   Differentiation—Under controlled conditions, stem cells may be guided to develop into sperm-like or egg-like cells.
4.  Application—These cells are then used in assisted reproduction procedures such as IVF (In Vitro Fertilization)

 According to PubMed 2024 research, stem cell–based therapies show potential in restoring spermatogenesis in men and improving ovarian response in women. However, these remain experimental and require specialist expertise.

Ovarian Rejuvenation Therapy, also known as Autologous Stem Cell Transplant in the Ovary (ASCOT), is an innovative treatment designed to enhance ovarian function.

This therapy is particularly beneficial for women with conditions like premature ovarian failure, low AMH levels / poor ovarian reserve, or age-related infertility (35–40+)

How Does Ovarian Rejuvenation Work?

The procedure involves injecting stem cells or Platelet-Rich Plasma (PRP) directly into the ovaries. These cells stimulate the regeneration of ovarian tissue, improving egg quality and quantity. The process can also delay menopause and alleviate symptoms of ovarian aging.

1.  Evaluation—A fertility specialist reviews medical history, hormone levels, and ovarian reserve.
2.  Extraction—PRP is prepared from the patient’s own blood, or stem cells are collected (usually from bone marrow).
3.  Preparation—PRP or stem cells are processed and enriched.
4.  Transplantation—Using a minimally invasive laparoscopic procedure, PRP or stem cells are injected directly into the ovarian tissue.
5.  Recovery & Monitoring—Patients usually return home the next day, and follow-up hormone tests are used to track improvement.

Shree IVF Clinic in Mumbai is among the few in India offering ASCOT (Autologous Stem Cell Transplant in the Ovary), where ovarian stem cells are reintroduced to encourage regeneration.

At Shree IVF Clinic in Mumbai, Dr. Jay Mehta and his team have pioneered ovarian rejuvenation using both PRP and stem cell techniques, with patients traveling from across India and abroad for treatment.

For Men:

• Increases sperm count through enhanced spermatogenesis.
• Repairs testicular tissue to improve sperm quality.

For Women:

• Stimulates ovarian tissue to produce healthier eggs.
• Repairs uterine tissue, improving implantation success rates.
• Delays menopause and alleviates symptoms of ovarian aging.

Success Rates and Limitations

According to recent research (PubMed 2023–2025):

• Stem Cell Therapy in IVF has shown potential improvements in sperm regeneration and oocyte quality, but long-term data is still limited.
       
• Ovarian Rejuvenation with Stem Cells/PRP shows around 15–20% improvement in ovarian response in early studies, though results vary by patient age and ovarian reserve.

👉 It’s important to understand that these therapies are not guaranteed cures but may enhance the chances of IVF success.

Limitations:

• Both treatments are considered experimental and may not work for everyone.
• Success rates are lower for women with ovarian failure or advanced age.

Risks & Considerations

• Still experimental—long-term safety under research

• Not suitable for everyone (especially advanced ovarian failure)

• Requires specialist expertise—not all clinics are qualified to perform these treatments. Always consult a qualified fertility doctor.

• Long-term safety and effectiveness are still under evaluation

Always ensure you are consulting a certified fertility specialist experienced in regenerative reproductive medicine.

The cost of these treatments in India can vary depending on:

• Complexity of the case (low ovarian reserve, premature ovarian failure, male infertility, etc.)
• Type of therapy (PRP vs. stem cell therapy)
• Additional IVF cycles or supportive treatments needed
• The clinic’s expertise and infrastructure

Since these are advanced and still experimental treatments, costs are typically higher than conventional IVF. The best way to know the exact investment is through a personalized consultation with your fertility specialist.

At Shree IVF Clinic in Mumbai, we provide transparent treatment planning and cost breakdowns so patients know exactly what to expect.

• Stem Cell IVF & Ovarian Rejuvenation are next-generation fertility treatments offering hope beyond standard IVF.

• They may help men with low sperm count and women with poor egg quality, low reserve, or POI.

• Still experimental—success depends on age, condition, and doctor expertise.

• Always consult an experienced fertility specialist before deciding.

If you’ve been struggling with infertility and want to explore advanced treatments like Stem Cell IVF Therapy or Ovarian Rejuvenation in India, the first step is a consultation with a trusted fertility specialist.

✨ Don’t lose hope—new science is opening new doors for parenthood.

👉 Book a consultation today at 1800-268-4000 and take your first step towards  new hope in fertility treatment