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Paternal Lymphocyte Immunization (PLI) at Shree IVF Clinic, Mumbai

Paternal Lymphocyte Immunization

Paternal Lymphocyte Immunization (PLI) emerges as a beacon of hope for couples navigating the challenging path of infertility.

This innovative treatment focuses on enhancing the female partner’s immune tolerance towards the paternal antigens, thereby improving the chances of a successful pregnancy. It is particularly beneficial for couples who have experienced recurrent miscarriages or multiple unsuccessful in vitro fertilization (IVF) attempts, suggesting a possible immune rejection of the pregnancy.

At Shree IVF Clinic in Mumbai, PLI is integrated into a spectrum of advanced fertility solutions, tailored to meet the unique needs of each couple. Under the guidance of seasoned fertility expert, Dr Jay Mehta, Shree IVF Clinic boasts a remarkable track record of success with PLI, offering not just a treatment but a renewed hope for couples dreaming of parenthood.

What is PLI?

Paternal Lymphocyte Immunization (PLI) is predicated on the intersection of immunology and reproductive medicine, addressing recurrent pregnancy losses and implantation failures attributed to maternal immune system resistance to paternal antigens.

The crux of PLI’s scientific foundation lies in its ability to modulate the maternal immune response, fostering an environment conducive to pregnancy. By introducing paternal lymphocytes into the maternal bloodstream, PLI essentially ‘trains’ the mother’s immune system to recognize and accept the paternal genetic material, rather than attacking it as foreign. This process not only improves the likelihood of successful implantation but also diminishes the risk of subsequent miscarriages.

The target audience for PLI consists primarily of couples who have endured the heartache of recurrent miscarriages or faced multiple failures in achieving pregnancy through in vitro fertilization (IVF), where paternal immune factors are suspected to be a contributing cause.

This innovative treatment holds the promise of overcoming such immunological barriers to pregnancy, offering these couples a ray of hope towards achieving successful parenthood.

Benefits of PLI at Shree IVF Clinic

Choosing Shree IVF Clinic for Paternal Lymphocyte Immunization (PLI) comes with a multitude of benefits, underscored by our outstanding success rates in improving implantation and achieving higher pregnancy rates.

At the heart of our success is a deeply experienced and highly qualified team of doctors and embryologists, who bring a wealth of knowledge and an empathetic approach to fertility treatment. Our specialists are dedicated to staying at the forefront of reproductive medicine, ensuring that each couple benefits from the latest insights and methodologies.

Our state-of-the-art facilities and advanced laboratory techniques are pivotal in the delivery of superior PLI treatment. Shree IVF & Endometriosis Clinic is equipped with cutting-edge technology that enables our team to perform PLI with the utmost precision and care, significantly enhancing the effectiveness of the procedure.

This meticulous attention to detail in every aspect of treatment fosters an environment where success rates are notably high, and couples are closer to achieving their dream of parenthood.

We understand that each couple’s fertility journey is unique. That’s why we pride ourselves on offering personalized treatment plans, meticulously tailored to meet the individual needs and circumstances of each couple. This personalized approach ensures that the treatment is not only effective but also aligned with the emotional and physical well-being of our patients.

At Shree IVF Clinic, our primary goal is to provide you with a supportive, understanding, and technologically advanced path to parenthood, making the process as smooth and stress-free as possible. Our commitment to these principles is reflected in our consistently high success rates and the confidence with which couples entrust us with their care.

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The PLI Procedure at Shree IVF Clinic

The Paternal Lymphocyte Immunization (PLI) procedure at Shree IVF Clinic is designed to be as smooth and stress-free as possible. Here’s a brief overview of what to expect:

  • Initial Consultation: Your journey begins with a comprehensive consultation with our team of fertility specialists. During this session, we will discuss your medical history, previous fertility treatments (if any), and your goals. It’s a perfect time for you to ask any questions and express any concerns you might have. Our aim is to make you feel informed and comfortable with the path ahead.
  • Pre-treatment Workup: Prior to starting the PLI process, a series of tests and screenings will be conducted to assess your health and fertility status. This may include blood tests, ultrasound scans, and a semen analysis for the male partner. These assessments help us tailor the PLI procedure to your specific needs, thereby increasing its success rate.
  • The PLI Procedure:

Begin by retrieving genetic material from embryos created through IVF.

  1. These embryos are then meticulously screened using advanced genetic testing techniques to identify any chromosomal abnormalities.
  1. Only healthy embryos with the correct number of chromosomes are selected for implantation.
  1. This minimally invasive and outpatient process ensures that the risk to both the mother and the embryos is minimal.
  • Post-procedure Care and Follow-Up: After the procedure, our team will provide you with detailed post-care instructions to ensure optimal recovery and the best possible outcome. Follow-up appointments are scheduled to monitor your health and the progress towards pregnancy. We remain committed to supporting you through every step of this exciting journey towards parenthood.

At Shree IVF Clinic, we understand that undergoing fertility treatments can be challenging. Rest assured, our dedicated team of experts will be with you every step of the way, committed to making your dream of becoming a parent a reality.

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Who is a Candidate for PLI?

The Paternal Lymphocyte Immunization (PLI) is particularly beneficial for couples who have faced challenges in their path to conceiving. Specifically, it offers hope to those with:

  • Recurrent Miscarriage or Implantation Failure: Couples who have experienced multiple miscarriages or failed embryo implantations can benefit greatly from PLI. This procedure enables the selection of embryos without chromosomal abnormalities, thus increasing the chances of a successful pregnancy.
  • Unexplained Infertility: For couples who have undergone extensive fertility testing without a definitive cause for their infertility, PLI can be a beacon of hope. By ensuring the embryos implanted are chromosomally healthy, it can potentially overcome unexplained barriers to achieving a pregnancy.
  • Certain Immunological Factors: Couples where one or both partners have been identified through testing to have immunological factors that could be contributing to infertility, miscarriage, or implantation failure can also benefit from PLI. In such cases, selecting genetically healthy embryos may mitigate the impact of these immunological challenges.

Our team at Shree IVF Clinic assesses each couple’s unique situation, guiding them through the decision-making process to determine if PLI is a suitable option for them. We are dedicated to providing you with all the necessary information and support to make the best choice for your family’s future.

Next Steps: Starting Your Journey with Shree IVF Clinic

Taking the first step towards expanding your family is monumental, and understanding all your options is crucial. If you’re considering Paternal Lymphocyte Immunization (PLI) or if you’re navigating challenges in your fertility journey, we’re here to support and guide you.

To explore how PLI could be part of your path to parenthood, we invite you to schedule a consultation with our dedicated fertility specialists at Shree IVF Clinic.

During your consultation, we’ll review your fertility history, and any challenges you’ve encountered, and discuss how PLI might fit into your personalized treatment plan.

For appointments and further inquiries, please contact us at +91 – 99209 14115

Your dream of growing your family deserves every opportunity to become a reality. Contact Shree IVF Clinic today, and take the next step in your fertility journey with a team that cares deeply about your success.

Dr. Jay Mehta Fertility and IVF Specialist In Mumbai

Dr. Jay Mehta

MBBS, DNB – Obstetrics & Gynecology
IVF & Endometriosis Specialist, Laparoscopic Surgeon (Obs & Gyn)

4.9

Verified & Most Trusted One

Dr. Jay Mehta is a renowned IVF specialist and fertility-preserving surgeon in Mumbai, India. He is the Director of Shree IVF and Endometriosis Clinic, as well as the Director of Uterine Transplant in Global Hospitals, Mumbai. He is a leading laparoscopic gynecologist in India for endometriosis and adenomyosis..

He is a well-known Fertility and IVF Specialist and also among few doctors in the country who specializes in Embryology and Andrology. He operates India’s major cities including Mumbai, Pune, Chennai, Hyderabad, Bangalore, Ahmedabad, Agra, Delhi etc.

To book an appointment, call: +91 - 9920914115 or fill out our contact form

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 Google Reviews

Ankita Katyal

I am incredibly grateful for Dr. Jay's exceptional support throughout my IVF journey. Dr Jay has been like God sent an Angel for us. From our very first meeting, it was clear that Dr. Jay was not only a highly skilled and knowledgeable professional but also someone who genuinely cared about my well-being.

From my first meeting, he was very clear transparent, and straightforward about my protocol, treatment line, and success rate. After two difficult IVF cycles that failed, I was beginning to lose hope.

However, Dr. Jay’s unwavering encouragement and meticulous care helped me stay positive and focused. Thanks to God and of course to his expertise and dedication, WE FINALLY ACHIEVED SUCCESS!!!!!

Krish A

Dr Jay Mehta is the best Fertility doctor. I am glad to have IVF done with Jay sir.

This unit is very ethical and very honest at work. In my previous IVF cycle, I did not have embryos in Chennai. I was here and Dr and team had told me not to worry. I was given end to end transparency about my embryos and I was lucky to become pregnant in the 1st cycle here, though I was told that the success rate will be about 25 to 30%.

IVF space is competitive, but these guys don't do any Ads on Google. And still if you search, Dr Jay is ranked no.1. I was extremely impressed with that and I am happy that I took a call to travel to Mumbai from Chennai.

I am thankful to the entire team for handling my case nicely. And May God shower the team with his choicest blessings.

Forum Shah

I visited 3 years back for my IVF treatment at that time and also got good treatment with Dr. Jay Mehta … the best part is he would tell me straight away whatever the cause and outcome would be.

This time also I came for Endometriosis treatment n within 3-4 days decided to get operated as there was no looking back as I trust him for his treatment. Thank you Dr once again for the right advice 😊

Deepak Jagadale

Dr Jay Mehta and team are simply excellent people and brilliant outcomes in Fertility services. Very very honest and humble doctor.

Thank you for the valuable guidance during the IVF process and the excellent and no hidden costs during IVF procedure. For middle class people it's a big relief.

Avinash Jain

Dr. Jay Mehta is a result-oriented specialist in his field and the best we could ask for, in a Metro city. His line of treatment for IVF is different from other IVF clinics.

The support provided by doctors and staff as well as all other attending doctors is phenomenal. We are very satisfied and will also highly recommend to others the IVF treatment at Shree IVF Clinic Mumbai.

Vijaya Garg

Dr. Jay Mehta is one of the best gynaecologist doctor of our India. I trust him faithfully and would like to recommend each and every one that don't waste time moving here and there to another doctorand .

I m sharing my experience I wasted my time mand oney by moving from one doctor to other and my problem was unsolved I'm thankful to Dr. Priyanka Shukla mam of trident hospital for suggesting Dr. Jay Mehta sir for my treatment . Now I'm pain-free...Thank you Dr. Jay Mehta sir... you are really my Boley baba shiv shsmbu. I m thankful to all the staff members of Shree IVF hospital

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