Best Male Infertility Treatment Doctor in Mumbai, India: Comprehensive Care at Shree IVF Clinic

Male infertility refers to a male’s inability to cause pregnancy in a fertile female, primarily due to issues with his sperm production or delivery.

This condition can stem from a variety of causes, including low sperm count (oligospermia), poor sperm motility (asthenozoospermia), abnormal sperm morphology (teratozoospermia), and issues with sperm delivery due to blockages, erectile dysfunction, or premature ejaculation.

In the majority of situations, it can be a combination of multiple such factors that may actually play a role in contributing to male fertility issues.

If you are searching for the best hospital & doctor in India for male infertility treatment, you must look for a center that combines advanced andrology with empathetic care.

At Shree IVF Clinic, led by Dr. Jay Mehta, we recognize that the biggest challenge in India is often the social stigma and “male ego.” Accepting the condition is the first step toward a successful cure.

Recognising the signs of male infertility can be challenging, as oftentimes, there are no noticeable symptoms. However, some common indicators might include

• Difficulty with ejaculation or changes in the volume of ejaculate
• Reduced sexual desire or difficulty maintaining an erection (erectile dysfunction)
• Pain, swelling, or a lump in the testicle area
• Decreased facial or body hair or other signs of a chromosome or hormone abnormality
• Frequent respiratory infections, as the immune system in men with fertility problems might be weakened.

It is essential to consult a doctor if you have been trying to conceive for over a year without success or have any of these symptoms. A comprehensive evaluation can help diagnose and treat male infertility effectively.

If you are asking, “Which doctor is best for male fertility?” it is essential to see someone who looks beyond a basic semen report. Dr. Jay Mehta is widely regarded as the best male fertility doctor in Mumbai, India, because of his deep expertise in hormonal and surgical interventions.

The biggest challenge in the domain of male infertility is not the treatment of the disease. It is actually the acceptance of the disease.

In a country like India, due to a high amount of male ego, it is extremely difficult for them to go ahead and accept the fact that they are otherwise infertile despite having other parameters of the body that are physically absolutely normal.

Due to the societal pressure, a lot of other issues may also pop up, which may prevent or inhibit them from taking the actual treatment, which is warranted by them.

Early diagnosis and timely intervention in male infertility are critical to improving the chances of successful conception—whether naturally or through assisted reproductive technologies (ART) such as in vitro fertilization (IVF).

Timely evaluation can identify reversible causes that can be treated medically or surgically, significantly improving outcomes.

Additionally, understanding the underlying cause of infertility can provide valuable information for a couple’s future family planning decisions.

Male infertility can arise from multiple factors, each affecting sperm production, function, or delivery in different ways. Understanding these causes is essential for accurate diagnosis and targeted treatment.

Varicocele 

Varicocele refers to the enlargement of veins within the scrotum, similar to varicose veins in the legs. It is one of the most common correctable causes of male infertility.

This condition disrupts normal temperature regulation of the testicles, which can reduce sperm count, motility, and overall quality. Surgical correction (varicocelectomy) may improve semen parameters and increase the chances of natural conception or better outcomes with assisted reproduction.

Hormonal Imbalances

Sperm production depends on a finely tuned hormonal system involving the hypothalamus, pituitary gland, and testicles. Even minor disturbances in this axis can significantly impair sperm creation.

Low testosterone, elevated prolactin, thyroid disorders, or pituitary dysfunction may all contribute to infertility. Treatment may include medications to stimulate natural hormone production or carefully monitored hormone replacement therapy.

Hormonal and endocrinological evaluation of the male partner is extremely important, especially in cases labeled as “unexplained infertility” or complex conditions like genetic or endocrine dysfunction (GED). Proper hormonal assessment also helps in planning injectable hormonal therapy when indicated.

Testicular Conditions

Certain testicular problems can directly impair sperm production, including undescended testicles (cryptorchidism),
Testicular cancer, Previous testicular surgery or trauma, infection-related damage.

Even after surgical correction or cancer treatment, sperm production may not fully recover. In such cases, assisted reproductive technologies (ART) may be required to achieve conception.

Ejaculation Issues

Ejaculatory disorders can prevent sperm from reaching the egg despite normal sperm production.

These include retrograde ejaculation (semen flows into the bladder instead of exiting through the penis), erectile dysfunction, premature ejaculation, and medical therapy. Behavioral treatment, or sperm retrieval techniques, can sometimes restore fertility potential.

Antisperm Antibodies

In some autoimmune conditions, the body mistakenly identifies sperm as foreign and produces antibodies that attack them. This can impair sperm movement and function, making fertilization difficult.

Specialized testing can identify this condition, and appropriate reproductive techniques can help overcome the barrier.

Blockages in the Reproductive Tract

Obstructions in the epididymis, vas deferens, or ejaculatory ducts can prevent sperm from being delivered during ejaculation.

These blockages may be

• Congenital (present from birth)

• Caused by infections

• Due to previous surgeries

• Resulting from trauma

Microsurgical correction can restore sperm flow in many cases. If correction is not possible, sperm retrieval combined with procedures such as Intracytoplasmic Sperm Injection (ICSI) may be recommended.

Lifestyle and Environmental Factors

Factors such as obesity, smoking, excessive alcohol use, exposure to toxins, and stress can negatively affect sperm production and quality. Lifestyle changes to address these factors can improve fertility in some cases.

Each of these causes presents its own set of challenges in diagnosing and treating male infertility.

A thorough examination by a male infertility specialist is crucial for identifying the specific cause and determining the most appropriate treatment plan.

For those looking for the top male infertility specialists in India, Shree IVF Clinic offers a high-volume center with advanced diagnostic mapping for all these conditions.

At Shree IVF, the first step in addressing male infertility involves a comprehensive evaluation.

This initial phase is crucial for understanding the underlying causes of fertility issues. We don’t just treat symptoms; we identify the root cause. It typically includes:

• Semen Analysis: This test evaluates several key factors of a man’s semen and the sperm contained within, such as count, motility (movement), and morphology (shape). Semen parameters are extremely valuable in deciding whether medical therapy, surgery, or ART is the best next step.

• Hormone Testing: Hormonal imbalances can significantly impact sperm production and health. Testing levels of testosterone and other hormones can provide insights into potential issues.

A lot of importance is to be given to the hormonal and endocrinology evaluation of the male partner because correct evaluation is important in a situation where there could be a system like unexplained infertility or GED.

Semen parameters are extremely beneficial in planning any form of injectable hormonal therapy for any of the male partners.

• Physical Examinations: A detailed physical examination helps in identifying varicoceles (abnormal enlargement of veins within the scrotum) and other possible physical causes of infertility.

When patients ask, “Which is the best clinic in Mumbai, India, for male infertility?” they choose us because of our 85% overall success rate in achieving pregnancy through ART for couples dealing with male factors.

Our goal at the Male Infertility Clinic in Mumbai is to offer a comprehensive range of treatment options tailored to address the specific causes of infertility identified during the evaluation process. These options include

• Medication Therapy: Depending on the underlying cause of infertility, different medications may be prescribed to improve hormone levels, improve testosterone levels, enhance sperm production, or address other specific issues.

In cases of endocrine dysfunction, carefully monitored hormonal therapy can significantly improve semen parameters and, in some men, restore natural fertility.

• Surgical Procedures: When infertility is caused by structural or anatomical problems, surgical intervention may be required

For conditions like varicoceles, obstructive azoospermia, or other anatomical abnormalities, surgical interventions may be necessary. These procedures aim to correct anatomical issues or retrieve sperm directly from the testicles or epididymis.

• Sperm Retrieval Techniques: In situations where sperm are absent in the ejaculate or ejaculation is not possible, advanced sperm retrieval methods are available.

  These include:

  • Testicular Sperm Extraction (TESE)—Direct extraction of sperm from testicular tissue.

  • Percutaneous Epididymal Sperm Aspiration (PESA)—Retrieval of sperm from the epididymis using a minimally invasive technique.

  Retrieved sperm can then be used in assisted reproductive technologies (ART) such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) to achieve fertilization.

• Lifestyle Modifications: Lifestyle plays a significant role in sperm quality. Recommendations may include dietary changes, adopting a healthy exercise routine, avoiding harmful substances, and reducing stress levels to improve overall sperm health and fertility.

• Varicocele Treatment: If varicocele is identified as a contributing factor, surgical correction (varicocelectomy) is often recommended.

This procedure improves blood flow within the scrotum, restores optimal temperature regulation, and may enhance sperm count, motility, and morphology.

Varicocele repair is one of the most effective surgically correctable causes of male infertility.

At our male fertility center, we prioritize creating individualized treatment plans that are meticulously tailored to each patient’s unique diagnosis and circumstances.

We understand that no two cases of infertility are identical—each comes with its own clinical findings, emotional concerns, timelines, and expectations.

Our approach is collaborative and patient-centered. After a thorough evaluation, we design a treatment strategy that directly targets the identified cause of infertility while also considering the broader picture of the patient’s life.

This personalized strategy ensures that the treatment path chosen not only addresses the specific medical issues at hand but also aligns with the patient’s lifestyle, preferences, and emotional well-being.

We also recognize that infertility treatment is not only a medical journey but an emotional one.

Therefore, our team remains actively involved at every stage—explaining findings clearly, discussing options transparently, and guiding patients through decision-making with confidence.

Shree IVF Clinic prides itself on its transparent and high success rates in treating male infertility.

With a comprehensive range of diagnostic tools and treatment options, our clinic has achieved remarkable outcomes.

• Overall Success Rate: Our clinic boasts an impressive overall success rate of 85% in achieving pregnancy through assisted reproductive technologies for couples dealing with male factor infertility.

  This reflects outcomes achieved through structured evaluation, targeted correction of reversible causes, and optimized use of procedures such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).

• TESE Success Rate: For men undergoing Testicular Sperm Extraction (TESE), we have observed a sperm retrieval success rate of 72%, which is significantly higher than the national average.

• Varicocele Surgery Outcome: Patients treated for varicoceles at our clinic have shown an 80% improvement in sperm quality and quantity, with 55% of these couples successfully achieving pregnancy naturally or through ART.

It’s important to note that while these statistics are encouraging, success rates can vary based on numerous factors, including the cause and severity of infertility, the age of the partner, and underlying health issues.

At our fertility clinic, we ensure patients are provided with realistic expectations based on their health profile and infertility diagnosis.

Our commitment to research, cutting-edge techniques, and personalized care continues to be the foundation of our success in helping couples achieve their dream of parenthood.

Varicocele is one of the most common correctable causes of male infertility. However, not every varicocele requires surgery. As a patient, it is important to understand when treatment is necessary and what realistic expectations should be.

At Shree IVF Clinic, we emphasize informed decision-making and individualized assessment before recommending any procedure.

1. Varicoceles Are More Common on the Left Side

Varicose veins of the testicle are significantly more common on the left side. This is due to anatomical differences in venous drainage between the left and right testicular veins.

Left-sided varicocele does not automatically mean it requires surgery. 

2. Not All Varicoceles Need Treatment

In the majority of cases, men do not require treatment unless:

• The varicocele is clinically palpable (felt on examination)
• It is causing pain or discomfort
• There is unexplained infertility with abnormal semen parameters

If the varicocele is small and not affecting sperm quality, treatment may not be necessary. 

3. Surgery Does Not Offer a 100% Guarantee

Varicocele surgery improves blood flow and temperature regulation in the testis, but it does not guarantee complete correction or pregnancy.

Success depends on:

• Severity of the varicocele
• Baseline sperm parameters
• Duration of infertility
• Female partner factors 

4. Expected Clinical Benefit

Statistically, approximately 30–40% of men show significant clinical improvement in semen parameters after varicocele surgery.

Improvement may include:

• Increased sperm count
• Better motility
• Improved morphology

However, not every patient experiences meaningful change. 

5. It Is a Minor Surgical Procedure

Varicocele repair (varicocelectomy) is typically a small procedure.

• No prolonged hospitalization is required
• Major bed rest is not needed
• Most men return to work within 2–3 days

Recovery is generally smooth with minimal downtime. 

6. Limited Benefit in Severe Asthenozoospermia

If the primary issue is severely poor sperm motility (asthenozoospermia), surgery may not provide a major benefit. In such cases, assisted reproductive techniques like Intracytoplasmic Sperm Injection (ICSI) may be more effective.

Proper patient selection is crucial before proceeding with surgery. 

7. Clinical Examination Is More Important Than Doppler Alone

We strongly prefer a detailed clinical examination over relying solely on scrotal Doppler ultrasound.

Scrotal Doppler is often performed in a supine (lying-down) position, which may underestimate the size and severity of the varicocele. Clinical examination in a standing position provides a more accurate assessment of the true nature and dimension of the condition.

Imaging is supportive—not definitive. 

8. A Detailed Discussion Is Essential

Before recommending surgery, we encourage every male patient to have a thorough discussion regarding:

• The realistic effectiveness of varicocele surgery
• Expected improvement timeline (usually 3–6 months)
• Whether surgery will meaningfully change the fertility plan
• Whether assisted reproductive treatment may still be required

Informed consent and clarity are essential before proceeding.

Varicocele surgery can be beneficial—but only in properly selected patients. It is not a universal solution for all cases of male infertility.

At Shree IVF Clinic, we focus on careful clinical evaluation, honest counseling, realistic expectation setting, and strategic decision-making

The goal is not just to perform surgery but to choose the option that genuinely improves your chance of achieving parenthood.

Antioxidant therapy is widely used in the management of male infertility, particularly when oxidative stress is suspected to affect sperm quality. However, as a patient, it is important to understand its role, limitations, and when it is truly beneficial.

At Shree IVF Clinic, we believe antioxidant therapy should be used strategically—not blindly or indefinitely.

1. Antioxidants Are Available Across Medical Systems

A wide variety of antioxidant therapies are available across different systems of medicine:

• Allopathic formulations
• Ayurvedic preparations
• Homeopathic supplements

Many of these aim to reduce oxidative stress, improve sperm motility, and enhance overall sperm health.

While multiple formulations exist, their effectiveness depends more on proper patient selection and monitoring than on branding alone.

2. Ayurvedic Antioxidants and Chyawanprash

In clinical experience, certain antioxidant-rich Ayurvedic preparations may offer broader vitality benefits. One such commonly used formulation is Chyawanprash, a traditional herbal preparation containing multiple natural ingredients (often around 30+ herbs).

It is widely available in India and is commonly taken as

• One spoon daily in the morning
• For general immunity, vitality, and antioxidant support

While it may support overall health and potentially sperm quality, it should not be considered a standalone treatment for severe male infertility.

3. Duration and Limitations of Antioxidant Therapy

Antioxidant therapy requires time to show measurable effects because sperm production cycles take approximately 72–90 days.

• Minimum recommended duration: 3 to 6 months
• Regular semen analysis monitoring is essential

However, patients must understand a critical limitation:

If sperm count is less than 5 million, antioxidant therapy alone is unlikely to produce meaningful improvement. In such cases, treatment may require:

• Injectable hormonal therapy
• Advanced evaluation
• Assisted reproductive techniques such as Intracytoplasmic Sperm Injection (ICSI)

4. Avoid Prolonged Unmonitored Therapy

One of the most common problems—especially in India—is prolonged use of antioxidant therapy without proper monitoring.

Many male partners:

• Continue supplements for years
• Switch brands repeatedly
• Visit multiple practitioners
• See little to no measurable improvement

Whether consulting allopathic, homeopathic, or Ayurvedic practitioners, therapy without objective semen analysis follow-up often leads to wasted time.

Before starting or continuing antioxidant therapy, consult a super-specialist in male infertility to ensure:

• Proper diagnosis
• Clear indication
• Defined treatment duration
• Measurable outcome tracking

5. Beware of False Hope

If anyone promises guaranteed improvement in sperm count or natural pregnancy solely through antioxidants, ask for that assurance in writing.

Most practitioners will hesitate—because antioxidant therapy is supportive, not curative.

Male infertility management requires:

• Evidence-based evaluation
• Clear hormonal assessment
• Realistic counseling
• Structured treatment planning

Currently, in countries like India, there are limited dedicated standardized guidelines for subclinical male infertility, which makes specialist guidance even more important.

Antioxidant therapy can be helpful—but only in selected cases and under supervision.

It is best suited for:

• Mild sperm parameter abnormalities
• Oxidative stress-related issues
• Adjunct support alongside medical treatment

It is not a miracle solution for severe male factor infertility.

The key is not just taking supplements—it is taking the right treatment, for the right patient, for the right duration, with proper monitoring.

Hormonal therapy in male infertility is not random or universal. It is based on structured classification and precise endocrine evaluation.

At Shree IVF Clinic, hormonal treatment is guided by a systematic approach known as the APHRODITE criteria, which helps categorize male patients and determine the most appropriate therapy.

This classification allows us to identify which hormonal pathway is affected and what form of intervention will provide the best outcome.

Category 1: Hypogonadotropic Hypogonadism (Low FSH & LH)

These are males who are suffering from hypogonadotropic hypogonadism. This could be either primary or secondary in nature, and it is characterized by low FSH and low LH values.

Both of them being typically less than 0.2, these are the males who suffer from extremely low sperm counts as well as temporary but reversible azoospermia.

Most of these males require long-term therapy with injection, HMG, and injection HCG, which is to be taken for a period of around 18 to 24 months. The earlier the treatment is initiated, the better it is for these patients.

The majority of them will get back to a normal sperm count and will end up having a normal conception, provided the female partner is absolutely normal.

Category 2: Normal Hormones but Poor Semen Parameters

These are males in whom there is a deteriorated semen parameter, but they have normal values of FSH and normal values of testosterone.

Recent developments and papers have shown that these males will benefit extremely well if they are given well-defined and curated therapy with recombinant FSH for a period of approximately six months.

If the female parameters are normal, then the couple will benefit extremely well. In this situation, the majority of the semen parameters would improve drastically.

Category 3: Low Testosterone with Normal FSH

These are males in whom there is hypogonadism with deranged semen parameters as well as a reduced value of testosterone, but the FSH is normal.

In this situation, I strongly recommend doing a clinical examination and the scrotal Doppler and ultrasound in order to find out the actual volume of the testis.

These are male patients who will greatly benefit from the hormonal therapy of injectable HCG 5000 international units to be administered intramuscularly once every week.

Intramuscularly, a strong recommendation is against giving an injection of testosterone in this situation because it can negatively affect the long-term feedback loop of sperm production.

Category 4: Compensated Failure (Elevated FSH, Low Testosterone)

These are males in whom there is compensation that has already occurred from the body where there is a deranged sperm parameter, and this is usually going to be in the range of non-obstructive azoospermia, and along with that, there is an elevated FSH value as well as reduced testosterone.

The majority of these males will usually not have a great long-term benefit, even if hormonal therapy is indicated for them.

They may usually end up with something called microTESE, which typically involves surgical retrieval of the sperm

Category 5: Unexplained Male Fertility 

This is a very big category, which includes a huge number of males who are suffering from infertility because quite a lot of them actually have normal sperm parameters.

Their wives also have normal parameters, and despite that, they are unable to conceive after having no form of sexual dysfunction. This category is very difficult to treat.

However, the role of recombinant FSH injection in this category is emerging very rapidly.

It has to be remembered by you as a patient that in order to have normal production of sperm from your testis, both the FSH and LH hormones are important to drive this correctly.

As a result of this, there could be a certain number of corrections that could be possible in these males.

This can be done by injectable therapy, and quite a lot of them would actually end up benefiting.

A lot of new data has shown that a six-month therapy with these hormonal injections would do a world of benefit to these males.

Deciding to proceed with in vitro fertilization (IVF) is a major emotional, medical, and financial step.

As a male partner, it is important to pause, understand your role in the process, and ensure that the decision is based on clarity—not pressure.

Here are key points you should carefully consider before moving forward

1. First of all, it is important to understand that accepting this therapy is very important for you to have peace of mind.

2. The majority of the commercial clinics will be pushing you into some of the other forms of treatment because they need to show numbers so that they can get the appropriate appraisal from their investors.

3. Please have categorical information in writing as far as the success rate of your situation and your case is concerned, because even in the best of situations, the live birth rate does not exceed approximately 40%.

A lot of times, assisted reproductive therapy may be indicated in your situation because the female partner may also be going through challenges.

4. A variety of techniques are available to ensure that the sperm that has been selected is the highest possible selection. These need to be followed in the clinic where you are performing your treatment, and as a result of this, kindly go down and dig deep into those types of questions before you pay the money and book the therapy.

The Sperm DNA Fragmentation Index (DFI) is an advanced diagnostic test that evaluates the integrity of genetic material inside the sperm.

While routine semen analysis checks count, motility, and morphology, DFI measures the quality of sperm DNA, which plays a crucial role in fertilization, embryo development, and pregnancy outcomes.

At Shree IVF Clinic, we recommend this test selectively, based on clinical indications—not routinely for every patient.

1. When Is DFI Testing Recommended?

DFI testing is particularly useful in cases of:

• Previous failed Intrauterine Insemination (IUI) cycles
• Repeated In Vitro Fertilisation (IVF) failures
• Prolonged unexplained infertility
• Abnormal semen parameters
• Recurrent early pregnancy loss

If standard tests do not explain repeated failures, DFI may provide deeper insight into sperm quality. 

2. It Is an Expensive Test—Choose the Lab Carefully

DFI testing typically costs around ₹14,000–₹15,000 in India.

Because treatment decisions may depend heavily on this report, it is important to:

• Get the test done at a reputable, specialized laboratory
• Ensure proper handling and processing
• Confirm standardized reporting methods

An inaccurate report can lead to unnecessary treatment or incorrect planning. 

3. Prefer Computer-Based Reporting

Ideally, DFI testing should be performed using a computer-based or automated platform.

Automated systems reduce human error and provide:

• Objective measurement
• Standardized scoring
• Greater reliability

Manual interpretation can introduce variability, so laboratory quality matters significantly. 

4. No Special Abstinence Required

Unlike routine semen analysis, DFI testing generally does not require prolonged abstinence before sample collection.

Your doctor may give specific instructions, but in most cases, no special preparation is required. 

5. How to Interpret DFI Values

Understanding the numbers is critical:

• DFI < 15% is then generally considered normal.
  • No treatment is usually required.
• DFI between 15–30% is then considered borderline.
  • Management depends on age, fertility duration, and female factors.
• DFI > 30% is then considered high fragmentation.
  • Requires individualized evaluation and targeted management.

Treatment decisions for high DFI are never based on the number alone. They depend on:

• Semen parameters
• Hormonal profile
• Duration of infertility
• Female partner’s fertility status
• Previous ART outcomes

Taking the first step toward your dream of parenthood is an important decision—and you don’t have to take it alone.

At Shree IVF Clinic, we are here to support and guide you at every stage of your fertility journey. To schedule a consultation and explore how our personalized treatment options can help you, simply call us at 1800-268-4000

Our experienced team will assist you with appointment booking, answer your questions, and ensure a smooth, comfortable process.

Whether you are dealing with male infertility, endometriosis, recurrent IVF failures, or unexplained infertility, we are here to provide structured guidance and evidence-based solutions.

Begin your journey to parenthood with confidence, knowing that your concerns will be addressed with compassion, expertise, and complete confidentiality.