Ovulation Induction

What is Ovulation Induction Treatment?
Ovulation induction is mainly a to-the-point treatment where hormonal pills are used for resuming ovulation. Sometimes having severe hormonal imbalance can lead to irregular periods. In the worst-case scenario, it can also lead to cysts in the ovary. Drugs used for ovulation induction treatment and women who cannot ovulate on their own take help of these. Moreover, ovulation induction helps in producing healthy eggs so that your ovary produces a healthy egg every month.
Everything You Need to Know About Ovulation Induction
Indications | Candidate | Medications | Process | What to expect | Risks & Symptoms | Side effects | Benefits | Preparation | Success rates | Cost | Results
Ovulation induction indications
If you are suffering from anovulation, opting for ovulation induction is the best option. At times, disorders like PCOS, poor nutrition, or too much workout can cause anovulation. After you start taking the medications, you will soon start facing some symptoms. For example, bloating, nausea, hot flashes, tenderness in the pelvic region, blurred vision, etc. If you feel uncomfortable with the symptoms, then it is best if you immediately consult doctors.
Who is ovulation induction suitable/recommended for?
Ovulation induction treatment is easy and safe to opt for by many women. For example, women suffering from infrequent ovulation or the ones who do not ovulate at all can opt for this treatment procedure. Doctors provide various fertility drugs based on the symptoms as well as the issues. Similarly, women having unexplained infertility issues can also opt for ovulation induction treatment. Fertility drugs are essential for those suffering from infertility. The reason behind this is it helps in increasing ovulation so that it becomes easy to conceive. Patients, undergoing IVF treatments also take ovulation induction medicine to increase the egg production rate.
Medications Used for Ovulation Induction
Various medications are used for ovulation induction treatment. The medications are mostly hormonal drugs that help in increasing the egg production rate. Clomiphene Citrate commonly known as Serophene or Clomid is the common hormonal medication. It is an oral medication and doctors recommend it to consume for five days. Doctors recommend fifty to a hundred mg per day; however, if the ovulation fails to occur, they increase the dosage. Clomiphene Citrate is an FDA approved medicine and it tricks your body to think that you do not have enough estrogen. Although it is quite an effective medicine, success depends on various factors like age, other fertility issues, or semen parameters.
Next, is letrozole, which is popularly known as Femara, which is yet another oral medicine useful for ovulation induction. Few studies showed that women who take Clomid and have ovulation induction could take Letrozole. Similarly, if you face any issues or side effects with Clomid, then you can switch to Letrozole. Initially, doctors recommend beginning the dosage with 2.5mg. However, if the ovulation fails, your doctor will increase the dosage.
Gonadotrophins are also useful when it comes to treating ovulation induction. But, it is different from that of Clomid or Letrozole. Gonadotropins are injectable drugs and the dosage continues for about five to twelve. Almost every patient is becoming comfortable with the concept of injecting Gonadotropins. The medication helps in allowing the follicles to mature; however, the dosage varies so that you can conceive. Besides, the threat of the risk of multiple births reduces as well. Doctors opt for the HCG injections that mimic the mid-cycle of LH surge.
The ovulation induction process
The process of ovulation induction is quite easy since the entire process of the treatment is quite straightforward. Doctors prescribe oral medications or hormonal injections for stimulating the ovulation procedure. Once your menstrual cycle begins, you can take the medications. However, the doctor will keep monitoring your body through ultrasound. It is important to understand that the entire process of ovulation induction is quite safe. Besides, doctors consider this treatment as one of the effective methods of treatment for removing fertility issues.
Step by Step Guide – ovulation induction
When opting for the ovulation induction procedure, it will include a few steps that are listed below.
- Stimulation– After taking the medicines, the drugs support the growth of the follicles carrying the eggs. Medicines normally replace the FSH so that the ovaries can produce high-quality eggs. Doctors keep tracking the follicular development as well as hormone levels through the stimulation cycle.
- Control– Soon after beginning the process, doctors recommend taking USG and blood tests so that they can track the medicinal effects. Apart from that, the tests also help in determining the hormonal levels along with the maturation status of the eggs. Doctors call the entire process follicular monitoring.
- Egg release– Once the follicles become ready and reach almost sixty to twenty millimeters based on the medications, doctors push HCG injection. Thus, you can get ready for intercourse or intrauterine insemination.
Treatment Options For Infertility

Infertility
Couples at a certain point in time have the desire to conceive. Many studies have found that almost 85% of the couples successfully conceive within one year of trying.

Infertility Assessment
Infertility assessments include various examinations as well as tests to find out the underlying reasons behind infertility.

IVF Treatment
In Vitro Fertilization, or IVF is a kind of fertilization where the eggs combine with sperm for fertilization outside the body.

Azoospermia Treatment
Azoospermia is a condition in men where the sperm count in their ejaculation is non-existent.

Follicular Study
Follicular study or follicular monitoring is the process through which the doctor watches the growth of this follicle from the beginning of the menstrual cycle to the time it is ready to release an egg.

ICSI
Intracytoplasmic Sperm Injection, which is also commonly known as ICSI is one of the common and most successful treatments for male fertility.

IMSI
Intracytoplasmic Sperm Injection is also known as IMSI is another procedure used during the time of IVF.

Stem Cell In IVF
In the whole world, around 8% to 12% of couples tend to get affected by the curse of infertility.

IUI
IUI, medically known as Intrauterine Insemination, is a simple form of fertility treatment.

Genetic Screening
Preimplantation Genetic Screening is a test that carefully examines the chromosomal material of an IVF or in-vitro fertilized egg before the process of implantation can begin.

CASA
Computer-Assisted Sperm Analysis or refers to a system where a complex electronic imaging system is used to visualize the sperm, while advanced software programs help measure the numerous individual parameters of said sperm.
What to expect during Ovulation Induction?
Once the treatment for induction ovulation starts, you might face some symptoms like hot flushes, nausea, pain in the pelvic region, etc. However, once the medicines successfully work, you will be able to have regular periods. If you were planning for pregnancy but failed due to infertility issues, you can easily conceive post-treatment. Alternatively, if you have been taking the IVF treatment, then the ovulation induction treatment will help in producing healthy eggs.
Risks, Symptoms associated with Ovulation Induction
Although the ovulation induction treatment is quite useful and effective, there are some associated risks as well. Almost two million women between the ages of fifteen to forty-four opt for fertility drug treatments. Few iatrogenic complications are there that come with the use of ovulation induction agents. Some of the common complications include preterm delivery and spontaneous abortion. Along with that, some severe complications include heterotopic pregnancy, chances of ovarian cancer as well.
Side effects of ovulation induction
Just like the uncountable benefits that infertile women get out of ovulation induction treatment, there are some side effects too. From abdominal distention to discomfort, bloating sensation, restlessness, and fatigue, you will come across many discomforts. Leaving them untreated can give rise to severe problems. Due to this reason, whenever you feel that the discomforts are increasing, you must immediately consult your doctor.
Benefits of ovulation induction
The only goal behind ovulation induction treatment is to make a woman fertile for conceiving. Even if you are not planning for pregnancy, opting for this treatment procedure will help in lowering the PCOS symptoms. When planning for conceiving, once the treatment completes, you can opt for normal intercourse. Apart from that, you can also opt for intrauterine insemination or other fertility treatments.
Preparing for ovulation induction
The preparation procedure of the treatment is quite simple. Your doctor will ask you to take different tests. Based on the results, they will suggest you taking hormonal medicines so that the effects of estrogen reduce. Thus, your body will be able to produce follicle-stimulating hormones. As a result, you will be able to conceive or have regular cycles. Doctors prescribe medicine like Clomiphene Citrate since it is one of the effective medicines for follicle stimulation.
Ovulation induction success rates
The success rate of ovulation induction depends on various factors like age, disease, diagnosis, etc. However, generally, almost twenty to twenty-five percent of women achieved successful results. Thus, women having PCOS or other infertility issues can get effective results from this treatment.
Ovulation induction Cost
The best part of the ovulation induction treatment is it is quite affordable. Almost everyone can opt for it. Single IUI ranges around three thousand. Hence, if you get the desired results within one cycle, then the overall cost will range around ten thousand. The entire cost will include tests, scans, and even medications.
Testing for pregnancy
If you take the pregnancy test after undergoing the treatment, then you can either opt for the at-home tests. Pregnancy kits are available that are quite handy. Alternatively, you go for a detailed check, HCG hormone in your urine. Once you conceive, your body produces HCG. In case you get a positive result on the first day of your cycle, then it is almost two weeks since your conception.
Chance of pregnancy with ovulation induction
As the ovulation induction treatment is quite effective, you can get pregnant after your treatment completes. However, the result again varies, and if you fail to get pregnant, it is better to consult your doctor.
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About Authors

Dr. Jay Mehta
Fertility and IVF Specialist
Dr. Jay Mehta is the Scientific Director of Shree IVF Clinic. He is a well-known Fertility and IVF Specialist and also among few doctors in the country who specializes in Embryology and Andrology.