Lymphocyte Immunization Therapy (LIT) at Shree IVF Clinic, Mumbai

A personalized approach to overcome immunological barriers for a successful IVF pregnancy
Lymphocyte Immunization Therapy (LIT) is an innovative treatment aimed at enhancing the chances of a successful pregnancy, especially in the context of In Vitro Fertilization (IVF). At its core, LIT involves using a patient’s own immune cells, or lymphocytes, to improve their body’s acceptance of an embryo.
This process begins with the extraction of lymphocytes from the prospective father or a donor, which are then processed and introduced into the maternal body. This exposure is designed to train the mother’s immune system to recognize these cells as friendly, thereby reducing the likelihood of the immune system attacking the embryo post-IVF.
One of the remarkable benefits of LIT for IVF patients is the significantly reduced risk of miscarriage. By promoting a harmonious immune response, LIT makes the uterine environment more conducive to embryo implantation. This not only enhances the chances of implantation but also contributes to higher overall pregnancy rates among participants.
Given these advantages, Lymphocyte Immunization Therapy represents a beacon of hope for many couples facing immunological barriers to achieving a successful pregnancy.
LIT at Shree IVF Clinic: A Beacon of Hope for Couples
Shree IVF Clinic, located in Mumbai, stands as a pioneer in offering Lymphocyte Immunization Therapy (LIT) as part of its comprehensive IVF services.
The clinic’s dedicated team of fertility specialists, immunologists, and support medical staff possess profound expertise in leveraging LIT to surmount immunological challenges in pregnancy. Driven by a deep understanding of reproductive immunology, Shree IVF Clinic employs state-of-the-art techniques and personalized treatment plans to ensure optimal outcomes for couples undergoing IVF.
With years of experience in administering LIT, Shree IVF Clinic has successfully aided countless couples in their journey towards parenthood, particularly those who have faced repeated IVF failures or unexplained miscarriages.
The clinic’s track record of improved IVF success rates, thanks to the integration of LIT, attests to its capability and excellence in fertility treatment. Shree IVF Clinic is not just committed to excellence but also to instilling hope and confidence in every couple that walks through its doors, seeking to realize their dreams of becoming parents.
The LIT Process: A Step-by-Step Guide
Step 1: Initial Consultation and Assessment
Your journey begins with an initial consultation at Shree IVF Clinic, where our specialists will assess your medical history and current health status to determine if LIT is a suitable option for you. This involves a thorough discussion about your IVF experiences and any immunological challenges you may have faced.
Step 2: Procuring Lymphocytes
Once you’re deemed a candidate for LIT, the next step involves the collection of lymphocytes. These immune cells are typically obtained from the prospective father or a donor. The process is safe and carefully performed under the guidance of our skilled medical team.
Step 3: Processing Lymphocytes
The collected lymphocytes undergo a meticulous preparation process in our state-of-the-art laboratory. Our aim during this step is to prepare the cells in a way that will be most beneficial for your treatment, ensuring the highest standards of safety and effectiveness.
Step 4: The Immunization Procedure
The prepared lymphocytes are then ready to be introduced into your body. This procedure is minimally invasive and conducted with the utmost care by our professionals. The goal here is for these cells to gently persuade your immune system to recognize and accept an embryo as part of your body.
Step 5: Monitoring and Follow-up
After the immunization, we closely monitor your response to the treatment. This includes regular check-ups to ensure your immune system is reacting as expected. The well-being of our patients is paramount, and we are committed to providing support throughout this empowering journey towards motherhood.
By understanding each step of the LIT process, we hope to provide you with the clarity and confidence to take this positive step forward in your IVF journey. At Shree IVF Clinic, we’re dedicated to making advanced treatments like Lymphocyte Immunization Therapy accessible and comprehensible, bringing you closer to the joy of parenthood.
Who Can Benefit from LIT?
Lymphocyte Immunization Therapy (LIT) is particularly beneficial for couples who have experienced recurrent implantation failure (RIF) or unexplained infertility.
Patients who fall into these categories might find that despite healthy embryos and a seemingly conducive uterine environment, pregnancy remains elusive.
RIF is typically defined as the occurrence of two or more failed embryo transfers, while unexplained infertility refers to cases where standard examinations and tests fail to reveal a discernible cause for a couple’s inability to conceive.
Couples facing these challenges often undergo multiple cycles of IVF without success, leading to emotional and financial strain. LIT offers a glimmer of hope by potentially addressing the immune response aspect of implantation failure.
It’s believed that in some patients, the woman’s immune system may mistakenly identify the embryo as a foreign threat, thereby preventing successful implantation. By introducing paternal or donor lymphocytes and promoting immune tolerance, LIT aims to create a more favorable environment for embryo implantation.
However, it’s essential for potential candidates to undergo a thorough evaluation by our fertility specialist, Dr. Jay Mehta to ensure LIT is a suitable option. This includes reviewing the patient’s medical history, previous IVF attempts, and current health status.
Our goal at Shree IVF Clinic is to offer personalized care tailored to the unique needs of each couple, guiding them toward the best possible treatment outcomes.

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Success Rates in LIT
The success rates of Lymphocyte Immunization Therapy (LIT) in enhancing IVF outcomes, while promising, can vary significantly among individuals.
Statistically, patients undergoing LIT have observed an increase in implantation and pregnancy rates, particularly those with a history of RIF or unexplained infertility.
Clinical studies and patient data have suggested improvements in live birth rates, with some reports indicating that up to 50% of previously unsuccessful couples conceive following LIT treatment.
However, it’s important to note that success rates are influenced by a myriad of factors including the age of the patient, the quality of embryos, and the precise nature of the infertility issue. At Shree IVF Clinic, we emphasize the importance of a comprehensive assessment to optimise treatment plans and enhance the likelihood of a positive outcome with LIT.
Next Steps
If you’re considering Lymphocyte Immunization Therapy (LIT) as a part of your fertility treatment plan, the team at Shree IVF Clinic is here to support you every step of the way.
To learn more about how LIT could enhance your chances of a successful pregnancy, we encourage you to reach out and schedule an initial consultation with one of our experienced fertility specialists. During this consultation, we will discuss your medical history, previous IVF attempts, and evaluate if LIT could be a suitable option for you.
To get started, please contact us at +91 – 99209 14115. Our friendly staff will guide you through the process and ensure you have all the information you need. At Shree IVF Clinic, your dream of parenthood is our priority, and we are committed to providing personalized care to help you achieve it.

Dr. Jay Mehta
MBBS, DNB – Obstetrics & Gynecology
IVF & Endometriosis Specialist, Laparoscopic Surgeon (Obs & Gyn)
Dr. Jay Mehta is a renowned IVF specialist and fertility-preserving surgeon in Mumbai, India. He is the Director of Shree IVF and Endometriosis Clinic, as well as the Director of Uterine Transplant in Global Hospitals, Mumbai. He is a leading laparoscopic gynecologist in India for endometriosis and adenomyosis..
He is a well-known Fertility and IVF Specialist and also among few doctors in the country who specializes in Embryology and Andrology. He operates India’s major cities including Mumbai, Pune, Chennai, Hyderabad, Bangalore, Ahmedabad, Agra, Delhi etc.
To book an appointment, call: 1800-268-4000 or fill out our contact form
Google Reviews

Ankita Katyal
I am incredibly grateful for Dr. Jay's exceptional support throughout my IVF journey. Dr Jay has been like God sent an Angel for us. From our very first meeting, it was clear that Dr. Jay was not only a highly skilled and knowledgeable professional but also someone who genuinely cared about my well-being.
From my first meeting, he was very clear transparent, and straightforward about my protocol, treatment line, and success rate. After two difficult IVF cycles that failed, I was beginning to lose hope.
However, Dr. Jay’s unwavering encouragement and meticulous care helped me stay positive and focused. Thanks to God and of course to his expertise and dedication, WE FINALLY ACHIEVED SUCCESS!!!!!

Krish A
Dr Jay Mehta is the best Fertility doctor. I am glad to have IVF done with Jay sir.
This unit is very ethical and very honest at work. In my previous IVF cycle, I did not have embryos in Chennai. I was here and Dr and team had told me not to worry. I was given end to end transparency about my embryos and I was lucky to become pregnant in the 1st cycle here, though I was told that the success rate will be about 25 to 30%.
IVF space is competitive, but these guys don't do any Ads on Google. And still if you search, Dr Jay is ranked no.1. I was extremely impressed with that and I am happy that I took a call to travel to Mumbai from Chennai.
I am thankful to the entire team for handling my case nicely. And May God shower the team with his choicest blessings.

Forum Shah
I visited 3 years back for my IVF treatment at that time and also got good treatment with Dr. Jay Mehta … the best part is he would tell me straight away whatever the cause and outcome would be.
This time also I came for Endometriosis treatment n within 3-4 days decided to get operated as there was no looking back as I trust him for his treatment. Thank you Dr once again for the right advice 😊

Deepak Jagadale
Dr Jay Mehta and team are simply excellent people and brilliant outcomes in Fertility services. Very very honest and humble doctor.
Thank you for the valuable guidance during the IVF process and the excellent and no hidden costs during IVF procedure. For middle class people it's a big relief.

Avinash Jain
Dr. Jay Mehta is a result-oriented specialist in his field and the best we could ask for, in a Metro city. His line of treatment for IVF is different from other IVF clinics.
The support provided by doctors and staff as well as all other attending doctors is phenomenal. We are very satisfied and will also highly recommend to others the IVF treatment at Shree IVF Clinic Mumbai.

Vijaya Garg
Dr. Jay Mehta is one of the best gynaecologist doctor of our India. I trust him faithfully and would like to recommend each and every one that don't waste time moving here and there to another doctorand .
I m sharing my experience I wasted my time mand oney by moving from one doctor to other and my problem was unsolved I'm thankful to Dr. Priyanka Shukla mam of trident hospital for suggesting Dr. Jay Mehta sir for my treatment . Now I'm pain-free...Thank you Dr. Jay Mehta sir... you are really my Boley baba shiv shsmbu. I m thankful to all the staff members of Shree IVF hospital
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