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IVF Treatment in Mumbai—Cost, Success Rates & Specialist Care by Dr. Jay Mehta
In vitro fertilisation (IVF) is the most effective assisted reproductive technology available.
Eggs are retrieved from a woman's ovaries, fertilized with sperm in our advanced embryology laboratory, and the resulting embryo is transferred directly into the uterus to establish a pregnancy.
At Shree IVF Clinic in Mumbai, IVF is performed under the direct clinical supervision of Dr. Jay Mehta, one of India's most sought-after IVF specialists, with over 12,000 IVF procedures performed across his career. Our approach is diagnostic-first: we identify why pregnancy has not occurred before we design your treatment, not after.
What is IVF Treatment?
IVF (In Vitro Fertilization), also called test tube baby treatment, is a medical procedure in which a woman's eggs and a man's sperm are combined outside the body in a specialized laboratory to create an embryo, which is then transferred into the uterus.
The term "in vitro" means "in glass," referring to the glass laboratory dish where fertilization originally took place. Today, the process uses advanced culture media and climate-controlled incubators that precisely replicate the conditions inside the human body.
IVF is used both as an infertility treatment and as part of gestational surrogacy. It is the most commonly performed and most successful of all assisted reproductive technologies (ART).
Key facts about IVF
- 13–17 million babies have been born worldwide through IVF since 1978 (Science Alert)
- One ART-conceived baby is born every 35 seconds globally
- 2.5–3.5 lakh IVF cycles performed in India annually, growing at ~15% per year
- Live birth rates of 40–52% for women under 35 at experienced Mumbai centres
- Frozen embryo transfer (FET) now accounts for ~50% of all IVF cycles globally
- A typical IVF cycle takes 4–6 weeks from start to pregnancy test
Who Needs IVF and When Should You Start?
IVF is recommended when natural conception or simpler fertility treatments like IUI have not succeeded or when specific medical conditions make IVF the most appropriate option.
A fertility specialist will evaluate both partners before recommending IVF.
Medical Conditions That May Require IVF to Get Pregnant
- Polycystic Ovarian Syndrome (PCOS)
Polycystic Ovary Syndrome (PCOS), often formally referred to as Polyendocrine Metabolic Ovarian Syndrome (PMOS), is the most common cause of ovulatory infertility, affecting 1 in 10 women.
In PCOS, multiple follicles develop in the ovaries, but ovulation is irregular or absent. When medication-based ovulation induction and IUI cycles fail, IVF with carefully calibrated stimulation protocols offers excellent results.
Success rates in PCOS patients under 35 can exceed 50% per frozen embryo transfer cycle.
- Endometriosis
Endometriosis causes uterine lining tissue to grow outside the uterus on the ovaries, fallopian tubes, and pelvic lining, leading to scarring, inflammation, and impaired fertility.
IVF is a strong option for women with endometriosis scarring, especially when combined with Dr. Mehta's fertility-preserving excisional surgery to remove the disease before the IVF cycle
- Tubal factor infertility
Scarred, damaged, missing, or blocked fallopian tubes prevent sperm from reaching the egg.
IVF completely bypasses the fallopian tubes by fertilizing the egg in the laboratory and transferring the embryo directly into the uterus, making it far more effective than surgical repair in most cases.
- Male factor infertility
Low sperm count (oligospermia), poor motility (asthenospermia), abnormal morphology, or no sperm count (azoospermia) are major reasons for infertility. IVF combined with ICSI, where a single sperm is injected directly into each egg, successfully overcomes most forms of male factor infertility.
Male factor infertility contributes to 40–50% of all cases.
- Unexplained Infertility
When all fertility tests return normal, but pregnancy has not occurred after 12 months (or 6 months for women over 35), the diagnosis is unexplained infertility. IVF identifies and resolves fertilization failures invisible in standard testing.
- Failed IUI Cycles
IUI (intrauterine insemination) has a 10–20% success rate per cycle. After 3–4 failed IUI cycles, IVF is the medically recommended next step with significantly higher success rates per attempt.
- Low Ovarian Reserve / Low AMH
Women with low Anti-Müllerian Hormone (AMH) have fewer eggs available. IVF's controlled stimulation retrieves as many eggs as possible in one cycle. Advanced protocols like DuoStim (dual stimulation within one menstrual cycle) can double egg yield in poor responders.
- Thin Endometrium
Women with a thin endometrium (uterine lining below 7mm) face difficulty with embryo implantation. IVF cycles at Shree IVF Clinic include endometrial preparation protocols, estrogen priming, PRP, and ERA testing to optimize the lining before transfer.
- Advanced Maternal Age (35 and Above)
Egg quality and quantity decline significantly after 35. Women aged 35–37 who have not conceived after 6 months, and women 38+ who have not conceived after 3 months, are advised to proceed to IVF promptly.
- Recurrent Pregnancy Loss
Women with two or more consecutive pregnancy losses benefit from IVF combined with Preimplantation Genetic Testing (PGT) to select chromosomally normal embryos, significantly reducing miscarriage risk.
- Genetic Disease Carriers:
Couples carrying hereditary conditions (thalassemia, cystic fibrosis, BRCA mutations) can use IVF with PGT-M to screen embryos before transfer, preventing transmission of the disease to the child.
IVF is also an excellent option for single women, LGBT couples, and oncology patients undergoing fertility preservation before chemotherapy or radiation. Call 1800-268-4000 to discuss your situation.
When Should You See an IVF Specialist in Mumbai?
Do not wait unnecessarily; earlier evaluation and treatment improve outcomes. You should consider seeing an IVF specialist if one or more of the following apply:
Consider IVF now if:
- You are under 35 and have been trying for 12+ months without pregnancy
- You are 35–37 and have been trying for 6+ months without pregnancy
- You are 38 or above; seek a fertility evaluation immediately (do not wait 12 months)
- You have been diagnosed with blocked or damaged fallopian tubes
- You have moderate-to-severe endometriosis (Stage III or IV)
- Your husband has severe oligospermia, azoospermia, or very high DNA fragmentation
- You have had 2+ failed IUI cycles
- You have a very low AMH (below 1.0 ng/mL)
- You have experienced 2 or more pregnancy losses
- You or your partner is a genetic disease carrier (thalassemia, cystic fibrosis, etc.)
- You are a single woman or LGBT couple planning a family
- You are about to undergo chemotherapy or radiation and want to preserve fertility
A fertility evaluation takes 1–2 weeks and includes a blood test, ultrasound, and semen analysis. You will leave the consultation with a clear diagnosis and a treatment plan, not just "keep trying."
📞 Not sure if IVF is right for you? Speak directly with Our Team: 1800-268-4000
IVF vs. IUI—Which Is Right for You?
| Factor | IUI | IVF |
|---|---|---|
| Fallopian tubes | Must be open | Not required |
| Sperm parameters | Mild issue only | Any severity (With ICSI) |
| Age | Under 35, short duration | 35+, or after failed IUI |
| Ovarian reserve | Normal | Low AMH suitable |
| Success rate per cycle | 10–20% | 35–55% (age-dependent) |
| Cost | ₹10,000–₹30,000 | ₹1,50,000–₹4,00,000 |
If you've been told IVF is your only option or if you've already had a failed cycle elsewhere, Dr. Jay Mehta offers a diagnostic-first approach. Before recommending IVF, we identify why pregnancy hasn't occurred. That changes outcomes.
How Does IVF Work? Step-by-Step Process
IVF is performed in clearly defined stages. The table below gives you the full timeline at a glance; detailed explanations for each step follow.
Step 1: Fertility Assessment & Pre-Treatment Testing (Week 1–2)
Before stimulation begins, both partners undergo a comprehensive fertility workup. This is not optional; it is what allows Dr. Mehta to design a protocol specific to your ovarian reserve, hormone profile, and history.
Tests for women:
- AMH (Anti-Müllerian Hormone) — ovarian reserve marker
- AFC (Antral Follicle Count) — transvaginal ultrasound
- Day 2–3 blood panel: FSH, LH, Estradiol
- TSH (thyroid), Prolactin, Fasting Insulin
- Hysteroscopy or saline sonography (uterine cavity check)
- Karyotyping (if recurrent pregnancy loss)
Tests for men:
- Semen analysis (count, motility, morphology)
- Sperm DNA Fragmentation Index (DFI) — if prior IVF failed
- Hormonal profile (FSH, LH, Testosterone) if sperm count is very low
- Karyotyping (if azoospermia or severe oligospermia)
Step 2: Ovarian Priming (1–2 Weeks Before Stimulation)
Some patients need ovarian priming before stimulation to synchronize follicle development. Options include oral contraceptive pills (OCPs), estrogen supplementation, or GnRH agonist (long protocol). Women with low ovarian reserve may skip this step.
Step 3: Ovarian Stimulation (8–14 Days)
Injectable FSH (gonadotropin) medications encourage the ovaries to develop multiple mature follicles simultaneously, rather than the single egg produced in a natural cycle.
- FSH medications: Gonal-F, Follistim, Menopur
- GnRH antagonist (Cetrotide/Orgalutran): Prevents premature ovulation
- Trigger shot (HCG or GnRH agonist): Administered when lead follicles reach 17–20mm; retrieval is scheduled precisely 36 hours later
Monitoring during stimulation: Transvaginal ultrasound + blood estradiol every 2–3 days. Dosage adjustments are made based on your response. Expect 4–6 clinic visits during this phase.
Common side effects: bloating, mild pelvic pressure, breast tenderness, and mood changes. Report severe pain or rapid weight gain immediately; these may signal OHSS.
Step 4: Egg Retrieval (20–30 Minutes)
A thin needle is guided through the vaginal wall under transvaginal ultrasound to aspirate eggs from each follicle. Performed under IV sedation, no incision, no general anesthesia. Patients return home the same day.
- Average eggs retrieved: 8–15 (normal reserve)
- Eggs are immediately assessed by the embryologist
Step 5: Sperm Collection & Preparation
The male partner provides a semen sample on the retrieval day. Sperm washing separates motile, healthy sperm from seminal fluid.
For azoospermia (no sperm in ejaculate):
- TESA: Fine needle aspiration from the testicle
- PESA: Sperm from the epididymis
- Micro-TESE: Microsurgical sperm extraction from seminiferous tubules for non-obstructive azoospermia
Step 6: Fertilization & Embryo Culture (Days 1–6)
Eggs are fertilized via:
- Conventional IVF: Eggs and sperm are placed together in a dish
- ICSI: A single sperm is injected directly into each egg used for male factor, poor prior fertilization, or surgically retrieved sperm
Embryo development:
| Day | Stage | Notes |
|---|---|---|
| Day 0 | Mature egg (MII) | Retrieved and assessed |
| Day 1 | 2-Pronuclei (2PN) | Fertilization confirmed |
| Day 3 | 8-cell embryo | Cleavage stage — can transfer here |
| Day 5 | Blastocyst | Optimal stage, higher implantation rates |
| Day 6 | Expanded blastocyst | Best stage for PGT biopsy or freezing |
Why culture to blastocyst (Day 5)? Blastocyst transfer achieves 40–50% implantation rates vs. 25–35% for Day 3 transfer because only the most developmentally competent embryos survive to this stage.
Step 7: Embryo Transfer (5–10 Minutes)
A thin catheter is guided through the cervix into the uterus under abdominal ultrasound, and the embryo is gently released. No anesthesia needed. Most patients describe it as similar to a cervical smear.
Fresh vs. Frozen Embryo Transfer:
| Fresh Transfer | Frozen Transfer (FET) | |
|---|---|---|
| Timing | Day 3 or 5 post-retrieval | 1–3 months later |
| Success rate | 35–45% | 40–55% (increasingly preferred) |
| When preferred | Normal response, no OHSS risk | OHSS risk, PGT required, progesterone elevated |
At Shree IVF Clinic, Dr. Jay Mehta individualizes the fresh vs. frozen decision. A "freeze-all" strategy is followed whenever safety or receptivity may be compromised.
Single Embryo Transfer (SET): Shree IVF follows evidence-based SET guidelines—one high-quality embryo in the right patient achieves equivalent success rates while eliminating twin pregnancy risks.
Step 8: Luteal Phase Support (Days 1–14 Post-Transfer)
Progesterone suppositories or injections maintain the uterine lining to support implantation. Estradiol, low-dose aspirin, and immunosuppressants (where indicated) may be added. Medications continue until the pregnancy test and, if positive, through 10–12 weeks.
Step 9: Pregnancy Test (14 Days After Transfer)
A serum beta-HCG blood test is performed 14 days after transfer, more accurate than a home urine test. If positive (Beta-HCG > 25 mIU/mL), a transvaginal ultrasound is scheduled at 6–7 weeks to confirm a heartbeat.
Complete IVF Timeline
| Week | Phase | What Happens |
|---|---|---|
| Week 1–2 | Assessment + Priming | Fertility tests, protocol design, OCP priming if needed |
| Week 3–4 | Ovarian Stimulation | Daily FSH injections, monitoring visits every 2–3 days |
| Day 1 of Week 5 | Egg Retrieval + Fertilization | OPU procedure, sperm collection, ICSI/IVF in the lab |
| Days 1–6 of Week 5 | Embryo Culture | Embryos observed daily; blastocyst selection on Day 5–6 |
| Day 5 or 6 | Embryo Transfer or Freeze | Fresh transfer or vitrification for FET cycle |
| Days 7–14 Post-Transfer | Luteal Support + Wait | Progesterone and estrogen: avoid strenuous activity |
| Day 14 Post-Transfer | Pregnancy Test | Serum Beta-HCG blood test |
Timeline may vary depending on whether a frozen embryo transfer cycle, PGT genetic testing, or ERA endometrial testing is required.
IVF Success Rates at Shree IVF Clinic Mumbai
The question patients ask most often is about IVF success rates.
The honest answer is that the chance of success from a single IVF cycle depends largely on your age, fertility diagnosis, and individual circumstances, not just the clinic.
What matters more is the cumulative success achieved over multiple cycles, the quality of the embryos, and whether the underlying cause of infertility has been accurately identified before treatment begins.
At Shree IVF Clinic, we do not start stimulation until we have a clear understanding of why a previous IVF cycle or natural conception has not been successful.
— Dr. Jay Mehta, MBBS, DNB (Obstetrics & Gynecology)
Scientific Director & IVF Specialist, Shree IVF Clinic, Mumbai
IVF success rates depend primarily on a woman's age, ovarian reserve, embryo quality, and the underlying cause of infertility. The most meaningful measure is the live birth rate per embryo transfer, not a "positive test rate."
IVF Success Rates by Age (Live Birth Rate per Transfer)
| Woman's Age | Live Birth Rate per Transfer | Key Point |
|---|---|---|
| Under 35 | 45–55% | Highest success; optimal egg quality |
| 35–37 | 35–45% | Mild decline; proceed without delay |
| 38–40 | 25–35% | Significant decline; PGT-A strongly recommended |
| 41–42 | 15–25% | Donor egg IVF becomes a serious option |
| 43 & above | 5–10% | Own-egg success limited; donor eggs offer 50–65% |
Cumulative Success After Multiple Cycles (Women Under 38)
| IVF Cycles Completed | Cumulative Live Birth Rate |
|---|---|
| 1 cycle | 40–50% |
| 2 cycles | 60–65% |
| 3 cycles | 72–80% |
| 6 cycles | 85–92% |
A note on comparing success rates: Always ask for live birth rate per transfer, not "clinical pregnancy rate." These are different numbers. Clinics that report only positive test rates appear to have higher success but may include early losses. We report live birth rates.
What Affects Your Chances of IVF Success and What Can You Do About It?
No two IVF cycles are identical because no two patients are identical. These are the key variables that determine whether a cycle succeeds:
Medical Factors (What Your Doctor Addresses)
- Age — the single strongest predictor; egg quality declines steeply after 37
- Embryo quality—graded AA to BB at blastocyst; top-grade embryos achieve 50–60% implantation
- Endometrial thickness—7–10 mm at transfer is optimal
- Sperm DNA fragmentation—DFI below 15% is ideal; high DFI reduces fertilization and increases miscarriage risk
- Uterine cavity — fibroids, polyps, or adhesions must be treated before transfer
- Immunological factors—elevated NK cell activity or HLA matching issues can cause repeated implantation failure even with good embryos
- Stimulation protocol — wrong protocol = poor response; individualized dosing is non-negotiable
What Lifestyle Changes Can Improve Your Chances of IVF Success?
Evidence-based steps you can take before and during your IVF cycle to improve your chances:
3 Months Before Starting IVF:
- Take Methylfolate (not regular folic acid) + Vitamin D + CoQ10 (600 mg/day) daily to improve egg mitochondrial function
- Both partners quit smoking completely. Nicotine reduces egg quality and sperm DNA integrity
- Achieve a BMI between 20 and 28; both underweight and overweight reduce success rates
- Get a semen DNA fragmentation test if not done; high DFI can be treated before IVF starts
- Get TSH checked — undiagnosed hypothyroidism reduces implantation rates
During the IVF Cycle:
- Attend all monitoring appointments; missing a scan can mean missing the trigger window
- Administer injections at the same time each day
Eat a Mediterranean-style diet; avoid ultra-processed foods, trans fats, and high-glycaemic foods - Keep alcohol at zero from the stimulation day through the pregnancy test
- Maintain light activity (30-min daily walk) but stop high-impact exercise from egg retrieval onwards
- Sleep 7–9 hours; melatonin produced during sleep is a natural antioxidant that protects egg quality
After Embryo Transfer:
- Resume normal daily activity; bed rest is not recommended and has no evidence of benefit
- Avoid heavy lifting or strenuous exercise for 2 weeks
Take all luteal support medications exactly as prescribed; do not skip progesterone doses - Avoid home pregnancy tests before Day 14; early tests cause unnecessary anxiety with unreliable results
- If the cycle fails, ask for a full review before starting another cycle; do not repeat the same protocol
IVF Cost in Mumbai, India (2026): Transparent Pricing & What's Included
The cost of IVF treatment in Mumbai ranges from ₹1,50,000 to ₹2,80,000 for a basic cycle. Total costs, including medications, ICSI, and a frozen embryo transfer, typically range from ₹3,00,000 to ₹4,00,000.
At Shree IVF Clinic, we maintain complete transparency in all treatment costs with no hidden charges and no surprises.
Under the guidance of Dr. Jay Mehta, one of India's leading IVF specialists, we aim to provide affordable IVF treatment in Mumbai with a high success rate.
| Component | Approximate Cost (INR) | Included in the basic package? |
|---|---|---|
| Initial consultation + workup | ₹5,000–₹10,000 | Usually Included |
| Stimulation monitoring (ultrasound + bloods) | ₹15,000–₹25,000 | Usually Included |
| FSH stimulation medications | ₹40,000–₹80,000 | Usually Charged Separately |
| Egg retrieval procedure | ₹30,000–₹50,000 | Usually Included |
| IVF laboratory (fertilization + embryo culture) | ₹20,000–₹30,000 | Usually Included |
| Blastocyst culture (Day 5) | ₹5,000–₹10,000 | May Be an Add-On |
| Embryo transfer | ₹15,000–₹25,000 | Usually Included |
| Luteal support medications | ₹10,000–₹20,000 | Usually Charged Separately |
| ICSI (if required) | ₹15,000–₹25,000 | Additional Cost |
| Embryo freezing (vitrification) | ₹15,000–₹25,000 | Additional Cost |
| Frozen embryo transfer (FET) cycle | ₹50,000–₹80,000 | Separate Treatment Cycle |
| PGT-A genetic testing (per embryo) | ₹15,000–₹25,000/embryo | Advanced Add-On |
Estimated total (basic IVF + ICSI + medications): ₹1,80,000–₹2,80,000
Estimated total (IVF + PGT-A + FET): ₹3,00,000–₹4,50,000
Shree IVF Clinic welcomes patients from across Mumbai, Ghatkopar, Andheri, Powai, Thane, Navi Mumbai, Pune, Gujarat, and all of India, as well as international patients from the UAE, UK, USA, Canada, Australia, and Africa.
At Shree IVF Clinic, every patient receives a written cost estimate before treatment begins. No hidden charges. Call 1800-268-4000 to request yours, or WhatsApp 099209 14115 for a same-day response.
Financial Disclaimer: For the most accurate IVF cost estimate, please schedule a consultation, as every fertility journey is unique and treatment costs may vary based on individual medical requirements.
Please note that any initial estimates do not constitute the final cost; a comprehensive, itemized financial breakdown will be provided transparently by our team only after your formal clinical consultation and diagnostic review.
Advanced IVF Techniques at Shree IVF Clinic
Shree IVF Clinic offers the full range of advanced reproductive technologies. Dr. Mehta matches the precise technique to your diagnosis.
ICSI — Intracytoplasmic Sperm Injection
A single sperm is selected and injected directly into each egg. Used for any degree of male factor infertility. Fertilization rate: 70–85% of mature eggs.
IMSI — Ultra-High Magnification Sperm Selection
IMSI uses 6,000x magnification (vs. 400x in standard ICSI) to examine sperm nuclear morphology before injection, selecting sperm with fewer DNA defects. Recommended for recurrent IVF failure and high sperm DNA fragmentation.
PGT-A — Embryo Genetic Screening
Preimplantation genetic testing screens blastocysts for chromosomal abnormalities before transfer. Benefits: reduces miscarriage risk by up to 50%; improves live birth rate per transfer to 60–70% regardless of age. Recommended for women 38+, recurrent pregnancy loss, and recurrent implantation failure.
ERA — Personalized Embryo Transfer Timing
The Endometrial Receptivity Array identifies your exact window of implantation (WOI) — the 24-hour window when the endometrium is most receptive. Improves outcomes in patients with recurrent implantation failure despite good embryos.
Blastocyst Culture
The extended culture to days 5–6 selects only developmentally competent embryos. Associated with 15–20% higher implantation rates than Day 3 transfer.
DuoStim — Double Stimulation in One Cycle
Two egg retrievals within one menstrual cycle (follicular + luteal phase) for women with very low ovarian reserve. Can nearly double egg yield in poor responders compared to a single standard stimulation.
Assisted Hatching
A precise laser creates a small opening in the embryo's outer shell (zona pellucida), helping it implant. It is recommended for frozen transfers and women over 38.
Oocyte Spindle Assay
Real-time imaging of the egg's spindle structure before ICSI identifies the optimal injection point and avoids damage to the egg's DNA organisation machinery.
Stem Cell IVF Treatment
For patients with severely depleted ovarian reserve or premature ovarian failure, stem cell IVF treatment offers an emerging option to regenerate ovarian function before conventional IVF stimulation
What Are the Side Effects and Risks of IVF?
IVF is a safe procedure when performed by an experienced team. However, like all medical treatments, it carries risks that every patient should understand.
Common Side Effects (Expected)
| Side Effect | Cause | Management |
|---|---|---|
| Headaches | GnRH analogue or fertility hormones | Stay hydrated and use paracetamol if advised by your doctor. |
| Hot flushes | Downregulation medications | Usually expected and temporary. |
| Bloating or pelvic pressure | Enlarged ovaries during ovarian stimulation | Rest and maintain adequate hydration. |
| Breast tenderness | Progesterone support medications | Typically resolves after stopping the medication. |
| Mood changes or feeling emotional | Hormonal fluctuations during treatment | Counselling, stress management, and partner support may help. |
| Swelling or rashes at the injection site | Subcutaneous fertility injections | Rotate injection sites and apply ice before injections if recommended. |
| Light spotting after embryo transfer | Cervical handling during the procedure | Usually normal and not a sign of IVF failure. |
Rare but Serious Risks of IVF
- Ovarian Hyperstimulation Syndrome (OHSS)
OHSS occurs when the ovaries overrespond to stimulation. Mild OHSS (bloating, mild pain) occurs in 10–20% of cycles. Severe OHSS requiring hospitalization occurs in less than 1% when a GnRH antagonist protocol with an agonist trigger is used as standard practice at Shree IVF Clinic for high-risk patients.
Warning signs of severe OHSS — call immediately:
- Sudden weight gain >2 kg in 24 hours
- Severe abdominal pain or rapid distension
- Nausea, vomiting, inability to drink fluids
- Decreased urine output
- Shortness of breath
📞 Emergency line: 1800-268-4000
- Multiple Pregnancy:
Transferring more than one embryo increases the risk. Shree IVF Clinic recommends single embryo transfer (SET) to protect maternal and infant health.
- Ectopic Pregnancy
Risk of approximately 2–5% in IVF pregnancies — higher with prior tubal disease. Early Beta-HCG monitoring and follow-up ultrasound are essential.
- Premature Delivery
Multiple pregnancies carry a higher risk of premature birth. SET policy directly reduces this risk.
IVF for Special Cases
IVF with Donor Eggs
When a woman's own eggs cannot be used (very low AMH, premature ovarian failure, age 43+, or genetic disease), donor egg IVF offers 50–65% live birth rates per transfer, the highest of any fertility treatment, regardless of the recipient's age.
All donors at Shree IVF Clinic undergo rigorous genetic, infectious disease, and psychological screening per ICMR guidelines.
IVF for Endometriosis
Dr. Jay Mehta's excisional endometriosis surgery, removing all disease while preserving healthy ovarian tissue, followed by IVF, delivers significantly better outcomes than IVF alone for Stages III–IV endometriosis. Most patients proceed to IVF within 3–6 months of surgery.
IVF for Azoospermia
For men with obstructive azoospermia (blocked ducts), sperm are retrieved via PESA or TESA. For non-obstructive azoospermia (very low sperm production), micro-TESE microsurgery identifies and extracts viable sperm even when standard retrieval fails. Retrieved sperm is used in ICSI immediately or cryopreserved.
IVF for Recurrent Pregnancy Loss
Couples with 2+ pregnancy losses undergo a dedicated RPL workup (chromosomal, uterine, thrombophilic, immunological).
IVF with PGT-A selects chromosomally normal embryos. Immune-related implantation failure is treated with prednisolone, tacrolimus, intravenous immunoglobulin (IVIG) treatment, or Intralipid infusions under our reproductive immunology program.
IVF for PMOS/PCOS
Modified low-dose stimulation protocols, a GnRH agonist trigger, and a freeze-all strategy eliminate virtually all severe OHSS risk in PCOS patients.
Success rates in PCOS patients under 35 are among the highest of any diagnostic group.
IVF for LGBT Couples and Single Women
IVF is available for same-sex female couples (reciprocal IVF / partner egg IVF with donor sperm) and single women (donor sperm IVF).
Legal and ethical counseling is provided before treatment.
IVF After Failed Cycles Elsewhere
Many patients arrive at Shree IVF Clinic after 2–4 failed IVF cycles at other centers.
Before recommending another cycle, Dr. Mehta conducts a full review of previous protocols, embryo grading records, sperm DNA fragmentation, the uterine cavity, and immune factors. A failed IVF is diagnostic information; it tells us where to look next.
What to Do After a Failed IVF Cycle?
A failed cycle is not a dead end; it is diagnostic information. The most important step after failure is a structured debrief, not an immediate repeat of the same protocol.
At Shree IVF Clinic, every failed cycle is followed by:
- A full review of the stimulation response, egg numbers, fertilization rate, and embryo grading records
- Evaluation of endometrial receptivity if implantation failed despite good-quality embryos
- Sperm DNA fragmentation re-assessment if fertilization was poor
- Immunological investigation if there is a pattern of failed transfers with good embryos
- A revised protocol before the next cycle, never a copy-paste of what did not work
How soon can you try again? Most patients can begin a second IVF cycle within 4–8 weeks of a failed first cycle, once the ovaries have recovered and the review is complete. Your body does not need to "rest" for months; that is a common myth. The clinical review, not the calendar, should drive the timing.
Patients traveling to Shree IVF Clinic after failed IVF elsewhere: Dr. Jay Mehta regularly evaluates and treats patients who have experienced repeated failure at other clinics.
Bringing your complete records from previous cycles, stimulation charts, egg count, fertilization reports, embryo grades, and transfer reports allows for a more precise second-opinion assessment. Call 1800-268-4000 to arrange a second-opinion consultation.
Emotional & Psychological Support During IVF
IVF is as emotionally demanding as it is physical. Shree IVF Clinic treats psychological well-being as a central part of care, not an afterthought.
Research shows that emotional distress does not directly reduce IVF success rates, but it significantly affects a patient's ability to continue treatment, make informed decisions, and cope with failure. Unaddressed anxiety is one of the primary reasons couples discontinue IVF before achieving pregnancy.
What we offer at Shree IVF Clinic:
- Pre-treatment counselling session to set realistic expectations and build a support plan
- Nursing team available during stimulation to answer questions and provide reassurance
- Structured debrief with Dr. Mehta within 2 weeks of any failed cycle
- Peer support connection to other couples at similar stages
- Referrals to fertility-specialist psychologists for clinical anxiety or depression
Evidence-based ways to support yourself:
- Maintain light physical activity; walking and yoga during stimulation are well tolerated
- Eat a whole-food diet rich in healthy fats, antioxidants, and lean protein
- Communicate openly with your partner. IVF stress is highest when processed in isolation
- Avoid fertility forums during the two-week wait; other people's symptoms are not your symptoms
Why Patients from Across India and Around the World Choose Shree IVF Clinic?
Most patients who come to us have already tried IVF somewhere else. What they tell us is that they were given a protocol, not a diagnosis.
At Shree IVF, we treat infertility as a problem to be solved, not a procedure to be repeated."
— Dr. Jay Mehta, MBBS, DNB (Obstetrics & Gynecology)
Scientific Director & IVF Specialist, Shree IVF Clinic, Mumbai
| What We Offer | Why It Matters for You |
|---|---|
| 15+ Years of Experience | Fewer protocol errors, faster decisions when your cycle doesn't go to plan |
| 12,000+ IVF Procedures Performed | Pattern recognition, no algorithm replaces Dr. Mehta has seen your situation before |
| Advanced Embryology Lab (Mumbai, in-house) | Embryos cultured on-site in a climate-controlled lab, not sent to a third-party facility |
| Endometriosis + Reproductive Immunology Expertise | Rare combination at one clinic; most IVF centres outsource this or skip it entirely |
| High-Risk & Complex Case Expertise | Failed IVF, low AMH, recurrent loss, immune implantation failure are our core focus, not edge cases |
| International Patient Services | Patients from the UAE, UK, USA, Canada, and Australia choose Mumbai for lower cost, equivalent outcomes, and Dr. Mehta's expertise |
| Transparent Pricing, No Hidden Costs | Written estimate provided before treatment starts — no surprises at the billing counter |
Shree IVF Clinic is trusted by patients from around the world, many of whom come to us after experiencing failed IVF cycles elsewhere. As India's busiest self-cycle IVF clinic, we provide advanced fertility treatments, personalized care, and dedicated support for overseas patients.
If you are considering fertility treatment abroad, explore our complete guide to IVF in India for International Patients, covering treatment costs, success rates, the IVF process, and essential travel information to help you plan your journey with confidence.
Meet Dr. Jay Mehta—IVF Specialist in Mumbai, India
Dr. Jay Mehta, MBBS, DNB (Obstetrics & Gynecology), is the Scientific Director of Shree IVF Clinic, Mumbai.
He has performed over 12,000 IVF procedures and more than 2,500 surgeries annually across all specialties and is among India's few practitioners with combined expertise across IVF, excisional endometriosis surgery, reproductive immunology, and Mullerian anomalies.
Why this matters to you: Most fertility centres can do IVF. Very few can diagnose and treat the underlying conditions, endometriosis, immune implantation failure, uterine anomalies, and azoospermia, that cause IVF to fail. Dr. Mehta does both.
Areas of expertise:
- IVF & Assisted Reproduction: Full spectrum of fertility treatments, including IVF, ICSI, PGT, donor egg IVF, and surrogacy.
- Excisional Endometriosis Surgery: One of India's highest-volume endometriosis surgeons, managing advanced cases that can significantly impact fertility.
- Reproductive Immunology: Evaluation and treatment of immune-related implantation failure and recurrent pregnancy loss.
- Mullerian Anomalies: Expertise in rare congenital uterine conditions, including MRKH syndrome, uterine septum, and bicornuate uterus services that are not routinely available at most IVF centres.
- Azoospermia & Male Infertility: Advanced sperm retrieval procedures, including Micro-TESE, TESA, and PESA, performed in-house.
Dr. Mehta conducts consultations in Mumbai (Ghatkopar), Pune, Chennai, Hyderabad, Bangalore, Ahmedabad, and Delhi & regularly treats patients who travel from across India and overseas for specialized fertility care. 📞 Book a consultation with Dr. Jay Mehta: 1800-268-4000
Visit Our Clinic: Shree IVF Clinic, 5th Floor, Jayant Arcade, Mahatma Gandhi Road, Ghatkopar East, Mumbai 400077 (Telemedicine options available for out-of-city and international patients).
FAQ'S About IVF Treatment
What is the difference between IVF and ICSI?
IVF and ICSI differ only in how fertilization is achieved in the laboratory. In conventional IVF, eggs and sperm are placed together in a dish, and fertilization happens naturally.
In ICSI, a single sperm is injected directly into each egg under a microscope. ICSI is recommended for male factor infertility, poor fertilization in a prior cycle, or when surgically retrieved sperm is used.
What are the steps involved in IVF?
The IVF process includes:
(1) fertility assessment and pre-treatment testing
(2) ovarian priming
(3) ovarian stimulation with daily injections
(4) egg retrieval under sedation
(5) sperm collection and preparation
(6) fertilization via IVF or ICSI and embryo culture to Day 5
(7) embryo transfer or freezing
(8) luteal phase support medications
(9) pregnancy blood test 14 days post-transfer
What is the IVF process timeline?
An IVF cycle typically takes 4–6 weeks: 1–2 weeks of pre-treatment testing and priming, 8–14 days of ovarian stimulation with daily injections and monitoring, 1 day for egg retrieval, 5–6 days for embryo culture, embryo transfer on Day 3 or Day 5, and a pregnancy blood test 14 days after transfer.
A frozen embryo transfer cycle adds 4–6 additional weeks.
How many injections are involved in IVF, and how painful are they?
During ovarian stimulation, patients self-administer 1–2 subcutaneous injections daily for 8–14 days, typically 10–20 injections in total per cycle.
These are fine-needle injections into the abdomen, generally described as a mild sting rather than significantly painful.
Most patients adapt after the first 2–3 days. Rotating injection sites and using a chilled alcohol swab beforehand reduces discomfort.
Does IVF always result in twins?
No. Single embryo transfer (SET) is now routine at Shree IVF Clinic and reduces the twin rate to below 2%.
Does IVF guarantee pregnancy?
No, and any clinic that tells you otherwise is misleading you. IVF gives you the best medical chance of achieving pregnancy, but no single cycle guarantees success.
Live birth rates per cycle range from 45–55% for women under 35, declining with age. What IVF does guarantee is the most controlled, evidence-based path to pregnancy available.
Dr. Mehta's diagnostic-first approach is specifically designed to improve outcomes over multiple cycles by identifying why previous attempts did not succeed.
How many IVF cycles does it take to get pregnant in India?
Most patients who achieve pregnancy do so within 3 cycles. Cumulative success rates across 3 cycles reach 72–80% for women under 38.
The right protocol matters more than the number of cycles. A failed cycle with the wrong stimulation plan is not comparable to a well-designed cycle after a proper diagnostic review.
How many eggs do I need for a successful IVF cycle?
There is no fixed number, but retrieving 8–15 eggs from a normal-reserve cycle gives the best chance of having at least one high-quality blastocyst to transfer.
From 10 eggs, roughly 7–8 will be mature, 5–6 will be fertilized, and 2–3 will develop to the blastocyst stage.
Quality matters more than quantity. DuoStim protocols are available for poor responders to maximize egg yield.
Will IVF affect my natural fertility in the future?
No. IVF stimulation recruits eggs that the ovaries had already allocated for that cycle, but would normally reabsorb eggs that would have been lost regardless.
Multiple studies confirm that IVF does not deplete ovarian reserve faster than natural aging.
Can I do IVF with one ovary?
Yes. Women with a single ovary, whether from surgical removal, ovarian torsion, or a congenital condition, can undergo IVF. The remaining ovary can often produce sufficient eggs for a successful cycle, particularly with an optimized stimulation protocol.
Success rates are slightly lower than with two ovaries but remain meaningful, especially in women under 38. Dr. Mehta has extensive experience with single-ovary IVF cases. Call 1800-268-4000 to discuss your specific situation.
Can IVF cause cancer?
No. Extensive long-term research, including studies following IVF patients for 20+ years, has found no increased risk of ovarian, breast, uterine, or any other cancer from IVF medications or procedures.
The hormonal stimulation used in IVF is short-term and does not have the chronic hormonal exposure associated with cancer risk factors.
If you have a personal or family history of hormone-sensitive cancers, discuss this with Dr. Mehta before treatment. Your protocol can be adjusted accordingly.
Can IVF cause birth defects?
The rate of birth defects in IVF-conceived babies is slightly higher than in naturally conceived babies, approximately 4–5% vs. 3% in the general population.
However, this small difference is largely attributed to the underlying infertility conditions (particularly older parental age and male factor) rather than the IVF procedure itself.
Blastocyst culture and PGT-A genetic testing further reduce the risk by selecting chromosomally normal embryos before transfer..
What happens if IVF fails?
A failed IVF cycle means the embryo did not implant; it is not a sign of permanent failure. The important next step is a structured review, not an immediate repeat.
Dr. Jay Mehta conducts a debrief within 2 weeks of any failed cycle to analyze stimulation response, embryo quality, endometrial receptivity, and possible immunological factors before designing the next protocol.
Can low AMH make IVF impossible?
No. Low AMH reduces the number of eggs available but does not make IVF impossible. Modified protocols (mild stimulation, DuoStim) maximize egg yield in poor responders.
For very low AMH with poor stimulation response, donor egg IVF offers live birth rates of 50–65% regardless of age.
Can I work during IVF treatment?
Yes, most patients continue working through most of the IVF cycle. The stimulation phase is compatible with a full work schedule, though you will need to attend clinic 4–6 times for monitoring scans.
Plan to take 1–2 days off around egg retrieval (procedure day + recovery day) and 1 day off around embryo transfer. The two-week wait can be managed at a normal work pace.
Can I have sex during IVF?
During stimulation and after egg retrieval, it is best to avoid intercourse; the ovaries are enlarged and tender after retrieval. After embryo transfer,
Dr. Mehta will advise based on your specific situation. There is no strong evidence that abstaining during the two-week wait improves outcomes.
Is there an IVF diet? What should I eat?
No single food causes or prevents IVF success, but a Mediterranean-style diet—olive oil, legumes, fish, leafy greens, nuts, and antioxidants—is the best-supported dietary pattern for fertility.
Avoid ultra-processed foods, trans fats, and high-glycemic foods. Alcohol should be eliminated from stimulation day through the pregnancy test.
Caffeine below 200 mg/day is generally considered acceptable.
Can I exercise during IVF?
Light exercise (30-minute walks, gentle yoga) is encouraged during the stimulation phase.
After egg retrieval, high-impact exercise should be stopped completely until after the pregnancy test, as the enlarged ovaries are at risk of torsion with sudden movement.
After embryo transfer, resume normal daily activity; bed rest has no evidence of benefit.
How much does IVF cost in Mumbai?
A basic IVF cycle in Mumbai costs ₹1,50,000–₹2,50,000. Total costs including medications, ICSI, and a frozen embryo transfer cycle, typically range from ₹2,50,000–₹4,00,000.
At Shree IVF Clinic, all costs are disclosed upfront in writing with no hidden charges. Call 1800-268-4000 to request a personalized cost estimate
Is IVF covered by insurance in India?
As of 2026, most standard health insurance plans in India do not cover IVF. Some group corporate policies and maternity riders include partial coverage for fertility treatments.
It is worth contacting your insurer to ask specifically about ART coverage before starting treatment.
Shree IVF Clinic provides itemized cost documentation to support insurance claims where applicable.
Can I get a second opinion on my failed IVF cycle at Shree IVF Clinic?
Yes. Dr. Mehta regularly provides second-opinion consultations for patients who have undergone one or more failed IVF cycles elsewhere.
Bring complete records from previous cycles' stimulation charts, egg count, fertilization reports, embryo grades, and transfer reports. Consultations are available in person in Mumbai and via telemedicine for patients from outside the city or abroad. Call 1800-268-4000 to arrange one.
What is the best IVF clinic in Mumbai, India?
Shree IVF Clinic (Ghatkopar, Mumbai) is rated among Mumbai's leading fertility centres, trusted by patients from across India and internationally for complex cases including failed IVF, recurrent miscarriage, endometriosis, low AMH, and azoospermia.
Dr. Jay Mehta's combination of IVF expertise and surgical sub-specialisation distinguishes the clinic from standard IVF centres.
I live in Thane / Navi Mumbai / Andheri. Is Shree IVF Clinic accessible from where I am?
Yes. Our clinic is in Ghatkopar East, which sits on the Central Line and is well connected by road to most parts of Mumbai.
Patients regularly travel from Thane, Navi Mumbai, Powai, Chembur, Andheri, and Bandra for in-person consultations.
If you are coming from Borivali, Kandivali, or the Western suburbs and want to reduce travel during the monitoring phase, we offer telemedicine for initial consultations and follow-up reviews so your first visit to the clinic can be timed around egg retrieval or transfer, not routine scans.
Address: 5th Floor, Jayant Arcade, Mahatma Gandhi Road, Ghatkopar East, Mumbai 400077.
Can international patients undergo IVF at Shree IVF Clinic?
Yes. Shree IVF Clinic regularly treats patients from the USA, UK, Canada, Australia, the UAE, Singapore, and Africa.
IVF is legally available in India for married heterosexual couples, including foreign nationals. Pre-cycle telemedicine consultations are available so you can assess your treatment plan before traveling.
Some patients complete stimulation and retrieval in Mumbai, then return for the frozen embryo transfer on a second trip. Contact our team to discuss a schedule that fits your travel constraints.
What happens to unused embryos after IVF?
Good-quality surplus embryos are cryopreserved using vitrification, an ultra-rapid freezing method that preserves embryo integrity for years.
Frozen embryos can be used in subsequent FET cycles without repeating egg retrieval.
Couples decide in advance what to do with remaining stored embryos: continue storage, donate to another couple, donate for research, or allow them to expire.
Can I choose the sex of my baby through IVF?
Sex selection for non-medical reasons is illegal in India under the PCPNDT Act. PGT-A testing does identify the sex of embryos as a byproduct, but this information cannot be used for gender selection for social reasons.
Sex selection is only permitted when a family carries a sex-linked genetic disease (e.g., Duchenne muscular dystrophy or hemophilia) and only after approval from a genetic board.
Who is suitable for IVF treatment?
IVF is suitable for couples facing infertility due to blocked or damaged fallopian tubes, endometriosis, PCOS, male factor infertility, unexplained infertility, low ovarian reserve, recurrent pregnancy loss, or failed IUI cycles.
It is also an option for single women, LGBT couples, and genetic disease carriers.
What are the possible complications of IVF?
Complications may include OHSS, ectopic pregnancy (2–5% risk), multiple pregnancy if more than one embryo is transferred, premature delivery, and egg-retrieval discomfort.
Severe OHSS risk is less than 1% with modern GnRH antagonist protocols..
Are there side effects of IVF medications?
Yes. Common side effects include headaches, hot flashes, mood changes, bloating, breast tenderness, injection site reactions, and fatigue.
These are temporary and resolve after the cycle. Severe or sudden worsening symptoms, rapid weight gain, and severe abdominal pain should be reported immediately.
How can I take care of myself during IVF?
Get 7–9 hours of sleep nightly, eat a Mediterranean-style diet, eliminate alcohol, maintain light activity like walking and yoga, and stay socially connected.
Avoid high-impact exercise after egg retrieval. If you find the emotional burden difficult, speak with our counseling team. This is a fully supported part of your care at Shree IVF Clinic.
Dr. Jay Mehta
MBBS, DNB—Obstetrics & Gynecology
IVF & Endometriosis Specialist, Laparoscopic Surgeon (Obs & Gyn)
4.9
Verified & Most Trusted One
Dr. Jay Mehta is a highly renowned IVF specialist and fertility-preserving surgeon based in Mumbai, India. As the director of the Shree IVF and Endometriosis Clinic, Mumbai, he is recognized as one of India's leading laparoscopic gynecologists for the advanced treatment of complex conditions such as endometriosis and adenomyosis.
Dr. Mehta's expertise extends deeply into reproductive medicine; he is a well-known IVF specialist and among the few practitioners in the country with specialized knowledge in embryology, andrology, reproductive immunology, and Mullerian anomalies. Dr. Mehta conducts operations and consultations across India's major cities, including Pune, Chennai, Hyderabad, Bangalore, Ahmedabad, Agra, and Delhi. To book an appointment, call: 1800-268-4000
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DuoStim/ Dual Ovarian Stimulation in IVF
DuoStim IVF involves two ovarian stimulation phases in one cycle to increase egg yield, especially helpful in low AMH fertility cases.
