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Necrozoospermia- Dead sperms का इलाज – Dr Jay Mehta

UPDATED ON 06th NOV. 2023


Dr Jay Mehta

Scientific Director & IVF Specialist with 10+ years of experience






Fertility issues are not exclusive to women; men face their own set of reproductive challenges, one of which is necrozoospermia.

This condition, though less commonly discussed, can have a significant impact on a couple’s ability to conceive. Let’s dive deeper into understanding what necrozoospermia is, its causes, diagnosis, and the available treatment options.

What is Necrozoospermia?

Necrozoospermia is an infertility diagnosis that points to a stark reality where all the sperm present in a semen sample are dead or show no motility.

It’s a condition that typically remains unnoticed until a couple encounters persistent challenges in their quest to conceive. The implications of necrozoospermia are profound, as the vitality of sperm is a cornerstone of male fertility.

Sperm must be alive and motile to travel through the female reproductive system and fertilize an egg. When sperms are non-viable, natural conception becomes highly unlikely without medical intervention.

In necrozoospermia, a man may produce normal quantities of sperm, but the absence of living spermatozoa in ejaculate means that these sperm cannot function in fertilization.

This condition can be diagnosed through a semen analysis, which involves microscopic examination to assess the vitality of the sperm. A diagnosis is often followed by further tests to determine the possible cause and to explore the avenues for treatment.

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The Common Causes

Determining the cause of necrozoospermia is crucial for understanding the possible treatments and prognosis. Various factors may contribute to this condition:

  • Autoimmune Disorders: As the body’s natural defense mechanism against disease, the immune system sometimes misfires, targeting healthy cells—in this case, sperm cells—leading to their destruction.
  • Genetic Anomalies: Chromosomal irregularities or genetic mutations can impair sperm vitality.
  • Infections: Certain infections, particularly those involving the reproductive tract, can impact sperm health and lead to necrozoospermia.
  • Environmental Toxins: Exposure to heavy metals, radiation, or toxic chemicals can damage sperm.
  • Lifestyle Factors: Smoking, excessive alcohol consumption, and drug use can negatively affect sperm vitality.
  • Medical Treatments: Chemotherapy or radiation therapy for cancer can result in the temporary or permanent production of non-viable sperm.
  • Testicular Conditions: Issues such as varicocele, testicular torsion, or trauma can impact the production and vitality of sperm.
  • Hormonal Imbalances: An imbalance in hormones such as testosterone can affect sperm health.

Read More: Can Diabetes Cause Infertility in Males?


Diagnosing necrozoospermia typically involves a detailed semen analysis. This analysis assesses sperm vitality and checks for the percentage of live sperm.

A diagnosis of necrozoospermia is confirmed when there is 100% immotility, provided the semen sample has been properly collected and analyzed to rule out any procedural errors.

Treatment Options

Before discussing treatment, it’s essential to understand that in about 80% of necrozoospermia cases, the condition is irreversible. However, hope is not lost, as assisted reproductive technologies (ART) offer potential solutions.

Read More: Which Doctor To Consult For Male Infertility

Intracytoplasmic Sperm Injection (ICSI)

Intracytoplasmic Sperm Injection (ICSI) presents a beacon of hope for men diagnosed with necrozoospermia. This advanced reproductive technology bypasses the need for sperm to naturally penetrate the egg by directly injecting a single sperm into the egg’s cytoplasm.

The key advantage of ICSI is its ability to utilize sperm that are found to be viable but immotile, which can be retrieved directly from the testicular tissue.

This is particularly beneficial for necrozoospermia patients, where motility is compromised, yet some sperm may still be capable of fertilization.

The process requires precision and skill, as each sperm is individually selected and injected, offering a chance of conception even in severe cases of male infertility.

Testicular Sperm Extraction (TESE)

Testicular Sperm Extraction (TESE) coupled with Laser Stimulation takes the possibilities a step further. TESE involves the extraction of sperm by a fine needle directly from the testes, where sperm may be more intact than in the ejaculate.

Once extracted, these sperm are subjected to laser stimulation, a process where a focused light beam is used to encourage the activation of the sperm.

The reaction of the sperm tail, specifically bending, is an indicator of its viability. The laser does not harm the sperm but rather helps in identifying those with the potential for fertilization.

Although the success rates for fertilization with this technique range from 10 to 15%, it represents a critical option for those who otherwise might not have the opportunity to father a child biologically.

These techniques exemplify the remarkable advances in assisted reproductive technology, offering new avenues for achieving pregnancy in couples affected by male infertility factors.

Considering Donor Sperm

It’s worth noting that donor sperm is not the first line of thought for those diagnosed with necrozoospermia. With treatments like ICSI, many men with this condition still have a chance at biological fatherhood.

Consulting with a fertility specialist in Mumbai is crucial to explore all possible options before considering donor sperm.

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The Role of Lifestyle Changes

While medical interventions are at the forefront of treating necrozoospermia, lifestyle modifications can also play a supportive role.

Here’s a list of few lifestyle changes:

  • Autoimmune Disorders: The body’s immune system mistakenly targets and destroys sperm cells.
  • Genetic Anomalies: Abnormal chromosomes or gene mutations can lead to non-viable sperm.
  • Infections: Reproductive tract infections can adversely affect sperm vitality.
  • Environmental Toxins: Exposure to chemicals or radiation can damage sperm DNA and vitality.
  • Lifestyle Factors: Habits like smoking, excessive alcohol use, and drug abuse can deteriorate sperm health.
  • Medical Treatments: Cancer therapies like chemotherapy and radiation can result in necrozoospermia.
  • Testicular Conditions: Varicocele, torsion, or trauma can compromise sperm production and function.
  • Hormonal Imbalances: Disproportionate levels of hormones like testosterone can impact sperm health.
  • Parting Thoughts

    Necrozoospermia poses a unique challenge in the realm of male fertility, but modern medicine provides several avenues for overcoming this obstacle.

    With a combination of lifestyle adjustments and medical interventions, many men with necrozoospermia can still hope to achieve the dream of fatherhood.

    It is a journey that requires patience, resilience, and the support of dedicated medical professionals, but the possibilities are both real and encouraging. If you need any further information on the topic, feel free to reach out. Our experts are here to help out.


    Dr Jay Mehta

    Scientific Director & IVF Specialist with 10+ years of experience





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